A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection
Non-enzymatic glucose detection is an effective strategy to control the blood glucose level of diabetic patients. A novel hierarchical core–shell structure of nickel hydroxide shell coated copper hydroxide core based on copper foam (Ni(OH)<sub>2</sub>@Cu(OH)<sub>2</sub>-CF) w...
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| Language: | English |
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2024-12-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/15/1/47 |
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| author | Yueyun Huang Jiahua You Yingru Ding Yun Xie Ting Wang Fanglong Zhu Weiping Gong Zhenting Zhao |
| author_facet | Yueyun Huang Jiahua You Yingru Ding Yun Xie Ting Wang Fanglong Zhu Weiping Gong Zhenting Zhao |
| author_sort | Yueyun Huang |
| collection | DOAJ |
| description | Non-enzymatic glucose detection is an effective strategy to control the blood glucose level of diabetic patients. A novel hierarchical core–shell structure of nickel hydroxide shell coated copper hydroxide core based on copper foam (Ni(OH)<sub>2</sub>@Cu(OH)<sub>2</sub>-CF) was fabricated and derived from NiO@Cu<sub>2</sub>O-CF for glucose sensing. Cyclic voltammetry and amperometry experiments have demonstrated the efficient electrochemical catalysis of glucose under alkaline conditions. The measurement displays that the fabricated sensor exhibits a detection scale of 0.005–4.5 mM with a detection sensitivity of 4.67 µA/µM/cm<sup>2</sup>. It has remarkable response/recovery times in respect of 750 μM glucose (1.0 s/3.5 s). Moreover, the NiO@Cu<sub>2</sub>O-CF shows significant selectivity, reliable reproducibility and long-term stability for glucose determination, suggesting it is a suitable candidate for further applications. |
| format | Article |
| id | doaj-art-2c4c5280fa7b4704b6216dd9c5fb5898 |
| institution | Kabale University |
| issn | 2079-4991 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj-art-2c4c5280fa7b4704b6216dd9c5fb58982025-01-10T13:19:21ZengMDPI AGNanomaterials2079-49912024-12-011514710.3390/nano15010047A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose DetectionYueyun Huang0Jiahua You1Yingru Ding2Yun Xie3Ting Wang4Fanglong Zhu5Weiping Gong6Zhenting Zhao7Guangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaGuangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaGuangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaGuangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaGuangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaGuangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaGuangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaGuangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, ChinaNon-enzymatic glucose detection is an effective strategy to control the blood glucose level of diabetic patients. A novel hierarchical core–shell structure of nickel hydroxide shell coated copper hydroxide core based on copper foam (Ni(OH)<sub>2</sub>@Cu(OH)<sub>2</sub>-CF) was fabricated and derived from NiO@Cu<sub>2</sub>O-CF for glucose sensing. Cyclic voltammetry and amperometry experiments have demonstrated the efficient electrochemical catalysis of glucose under alkaline conditions. The measurement displays that the fabricated sensor exhibits a detection scale of 0.005–4.5 mM with a detection sensitivity of 4.67 µA/µM/cm<sup>2</sup>. It has remarkable response/recovery times in respect of 750 μM glucose (1.0 s/3.5 s). Moreover, the NiO@Cu<sub>2</sub>O-CF shows significant selectivity, reliable reproducibility and long-term stability for glucose determination, suggesting it is a suitable candidate for further applications.https://www.mdpi.com/2079-4991/15/1/47NiO-coated Cu<sub>2</sub>Onon-enzymaticelectrochemical glucose detection |
| spellingShingle | Yueyun Huang Jiahua You Yingru Ding Yun Xie Ting Wang Fanglong Zhu Weiping Gong Zhenting Zhao A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection Nanomaterials NiO-coated Cu<sub>2</sub>O non-enzymatic electrochemical glucose detection |
| title | A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection |
| title_full | A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection |
| title_fullStr | A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection |
| title_full_unstemmed | A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection |
| title_short | A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection |
| title_sort | hierarchical core shell structure of nio cu sub 2 sub o cf for effective non enzymatic electrochemical glucose detection |
| topic | NiO-coated Cu<sub>2</sub>O non-enzymatic electrochemical glucose detection |
| url | https://www.mdpi.com/2079-4991/15/1/47 |
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