Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional study
BackgroundPrevious studies have established a connection between obesity and obstructive sleep apnea (OSA), novel surrogate markers of adipose accumulation may serve as more critical and reliable factors for consideration. Consequently, this study aims to explore and elucidate the correlation betwee...
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1480717/full |
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| author | Xue Xu Jing Xu Mengye Zhang |
| author_facet | Xue Xu Jing Xu Mengye Zhang |
| author_sort | Xue Xu |
| collection | DOAJ |
| description | BackgroundPrevious studies have established a connection between obesity and obstructive sleep apnea (OSA), novel surrogate markers of adipose accumulation may serve as more critical and reliable factors for consideration. Consequently, this study aims to explore and elucidate the correlation between metabolic score for visceral fat (METS-VF) and OSA.MethodsIn this cross-sectional study, the data from the National Health and Nutrition Examination Survey (NHANES) during the period from 2013 to 2020 were adopted. Through multivariate logistic regression, restricted cubic spline regression (RCS), subgroup analyses and sensitivity analyses, the correlation between METS-VF and OSA was explored.ResultsAmong 8,284 subjects, 4,176 of them were categorized as having OSA. It was observed that the quartile range of METS-VF increased, with a notable rise in the prevalence of OSA (32.8% vs. 49.8% vs. 56.9% vs. 62.1%, p < 0.001). Logistic regression analyses showed a significant positive correlation between METS-VF and the risk of having OSA, even after accounting for potential confounders (OR = 2.436, 95% CI: 2.065, 2.874). Subgroup analyses further revealed a stronger correlation between OSA and METS-VF among subjects who were female, younger, and Mexican Americans. RCS regression identified a positive linear correlation, without threshold effects. Sensitivity analyses with stop breathing (OR = 2.283, 95%CI: 1.169, 3.070) or snoring (OR = 2.716, 95%CI: 2.273, 3.246) as outcomes reaffirmed the positive correlation with METS-VF.ConclusionElevated METS-VF demonstrated a linear correlation with the increased incidence of OSA, suggesting the potential utility as a predictive index for OSA. |
| format | Article |
| id | doaj-art-2c424cd8d78a41a0b41de1e4daa59d38 |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Medicine |
| spelling | doaj-art-2c424cd8d78a41a0b41de1e4daa59d382024-12-12T05:10:25ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-12-011110.3389/fmed.2024.14807171480717Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional studyXue Xu0Jing Xu1Mengye Zhang2Department of Rehabilitation Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, ChinaDepartment of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, ChinaBackgroundPrevious studies have established a connection between obesity and obstructive sleep apnea (OSA), novel surrogate markers of adipose accumulation may serve as more critical and reliable factors for consideration. Consequently, this study aims to explore and elucidate the correlation between metabolic score for visceral fat (METS-VF) and OSA.MethodsIn this cross-sectional study, the data from the National Health and Nutrition Examination Survey (NHANES) during the period from 2013 to 2020 were adopted. Through multivariate logistic regression, restricted cubic spline regression (RCS), subgroup analyses and sensitivity analyses, the correlation between METS-VF and OSA was explored.ResultsAmong 8,284 subjects, 4,176 of them were categorized as having OSA. It was observed that the quartile range of METS-VF increased, with a notable rise in the prevalence of OSA (32.8% vs. 49.8% vs. 56.9% vs. 62.1%, p < 0.001). Logistic regression analyses showed a significant positive correlation between METS-VF and the risk of having OSA, even after accounting for potential confounders (OR = 2.436, 95% CI: 2.065, 2.874). Subgroup analyses further revealed a stronger correlation between OSA and METS-VF among subjects who were female, younger, and Mexican Americans. RCS regression identified a positive linear correlation, without threshold effects. Sensitivity analyses with stop breathing (OR = 2.283, 95%CI: 1.169, 3.070) or snoring (OR = 2.716, 95%CI: 2.273, 3.246) as outcomes reaffirmed the positive correlation with METS-VF.ConclusionElevated METS-VF demonstrated a linear correlation with the increased incidence of OSA, suggesting the potential utility as a predictive index for OSA.https://www.frontiersin.org/articles/10.3389/fmed.2024.1480717/fullobesityMETS-VFBMIinsulin resistanceweightheight |
| spellingShingle | Xue Xu Jing Xu Mengye Zhang Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional study Frontiers in Medicine obesity METS-VF BMI insulin resistance weight height |
| title | Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional study |
| title_full | Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional study |
| title_fullStr | Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional study |
| title_full_unstemmed | Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional study |
| title_short | Association between metabolic score for visceral fat and obstructive sleep apnea: a cross-sectional study |
| title_sort | association between metabolic score for visceral fat and obstructive sleep apnea a cross sectional study |
| topic | obesity METS-VF BMI insulin resistance weight height |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1480717/full |
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