Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study

Abstract Depression has emerged as a significant public health concern, with its prevalence fluctuating based on varying environmental and demographic factors. This study categorized participants based on altitude. A convenient sampling approach was used, and the hamilton depression rating scale-24...

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Main Authors: Yuji Chen, Ga Long, Qing Huang, Ping Zhang, Nie Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-84357-5
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author Yuji Chen
Ga Long
Qing Huang
Ping Zhang
Nie Xu
author_facet Yuji Chen
Ga Long
Qing Huang
Ping Zhang
Nie Xu
author_sort Yuji Chen
collection DOAJ
description Abstract Depression has emerged as a significant public health concern, with its prevalence fluctuating based on varying environmental and demographic factors. This study categorized participants based on altitude. A convenient sampling approach was used, and the hamilton depression rating scale-24 was used to assess depressed symptoms while gathering demographic information. A total of 600 Tibetan residents from the Dege area of Garze Prefecture, Sichuan, China, participated in the survey. The mean age is 56.81 years, males comprising 52.8% and females 47.2% of the sample. Of the participants, 41.2% resided permanently at elevations exceeding 3500 m. The results found that the weighted prevalence of depression in the area was 24.62%. Regardless of gender, the age group with the highest prevalence was 55–64 years old. Depression increased with age as well as gradually decreased after the age of 60. Logistic regression analysis showed that middle-aged (OR 2.86, 95% CI 1.69–4.82, P < 0.01) and elderly people (OR 2.27, 95% CI 1.30–3.98, P < 0.01), living in ultra-high altitude areas (OR 3.48, 95% CI 1.35–2.91, P < 0.01) and low BMI (OR   4.31, 95% CI 1.33–13.93) are high-risk factors for depression. This study enhances the understanding of the characteristics of depression in high-altitude regions of China, contributing to a more comprehensive view of the psychological well-being of residents in these areas. The findings underscore the need for targeted prevention and treatment strategies tailored to the specific needs of these populations.
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spelling doaj-art-2c2e4b716b9d4b48bee154b6a5dd3f2b2025-01-05T12:19:39ZengNature PortfolioScientific Reports2045-23222025-01-011511810.1038/s41598-024-84357-5Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional studyYuji Chen0Ga Long1Qing Huang2Ping Zhang3Nie Xu4Department of Oncology, Chengdu First People’s HospitalInternal Medicine, Dege County People’s Hospital, Ganzi Tibetan Autonomous PrefectureDepartment of Radiotherapy, Sichuan Cancer Center, Sichuan Cancer Hospital & InstituteDepartment of Oncology, Chengdu First People’s HospitalDepartment of Oncology, Chengdu First People’s HospitalAbstract Depression has emerged as a significant public health concern, with its prevalence fluctuating based on varying environmental and demographic factors. This study categorized participants based on altitude. A convenient sampling approach was used, and the hamilton depression rating scale-24 was used to assess depressed symptoms while gathering demographic information. A total of 600 Tibetan residents from the Dege area of Garze Prefecture, Sichuan, China, participated in the survey. The mean age is 56.81 years, males comprising 52.8% and females 47.2% of the sample. Of the participants, 41.2% resided permanently at elevations exceeding 3500 m. The results found that the weighted prevalence of depression in the area was 24.62%. Regardless of gender, the age group with the highest prevalence was 55–64 years old. Depression increased with age as well as gradually decreased after the age of 60. Logistic regression analysis showed that middle-aged (OR 2.86, 95% CI 1.69–4.82, P < 0.01) and elderly people (OR 2.27, 95% CI 1.30–3.98, P < 0.01), living in ultra-high altitude areas (OR 3.48, 95% CI 1.35–2.91, P < 0.01) and low BMI (OR   4.31, 95% CI 1.33–13.93) are high-risk factors for depression. This study enhances the understanding of the characteristics of depression in high-altitude regions of China, contributing to a more comprehensive view of the psychological well-being of residents in these areas. The findings underscore the need for targeted prevention and treatment strategies tailored to the specific needs of these populations.https://doi.org/10.1038/s41598-024-84357-5TibetanDepressionHigh altitudeQinghai-Tibet plateau
spellingShingle Yuji Chen
Ga Long
Qing Huang
Ping Zhang
Nie Xu
Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study
Scientific Reports
Tibetan
Depression
High altitude
Qinghai-Tibet plateau
title Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study
title_full Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study
title_fullStr Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study
title_full_unstemmed Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study
title_short Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study
title_sort depression among tibetan residents in the southeastern region of qinghai tibet plateau a cross sectional study
topic Tibetan
Depression
High altitude
Qinghai-Tibet plateau
url https://doi.org/10.1038/s41598-024-84357-5
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