CT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in Serbia
Background/Aim. The corona virus disease 2019 (COVID-19) primarily affects the respiratory system, so radiological diagnosis has been shown to be necessary. Chest computed tomography (CT) is to be shown the best modality in suspected COVID-19 cases for initial evaluation because CT findings may be p...
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| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2021-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84502000125K.pdf |
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| author | Kosanović Tijana Mišović Miroslav Đukić Vladimir Lalošević Miodrag Đorđević Marjana Rančić Nemanja |
| author_facet | Kosanović Tijana Mišović Miroslav Đukić Vladimir Lalošević Miodrag Đorđević Marjana Rančić Nemanja |
| author_sort | Kosanović Tijana |
| collection | DOAJ |
| description | Background/Aim. The corona virus disease 2019 (COVID-19) primarily affects the respiratory system, so radiological diagnosis has been shown to be necessary. Chest computed tomography (CT) is to be shown the best modality in suspected COVID-19 cases for initial evaluation because CT findings may be present before the onset of symptoms. The aim of this study was to show different CT imaging features or patterns in COVID-19 patients with a different time course and disease severity. Methods. This prospective cohort study analysed 330 patients (the average age was 52.37 ± 15.36) with confirmed COVID-19 via laboratory testing. During hospitalization, all patients included in the study underwent chest CT in order to assess the extent of changes in their lungs. COVID-19 patients, with a different time course and disease severity, were classified into four categories: lung, bronchial, pleural and mediastinal changes. Based on the time interval between the onset of symptoms and performed CT scan, all patients were divided into three groups: group 1 (CT scans done ≤ 1 week after symptom onset); group 2 (from > 1 to 2 weeks after symptom onset); group 3 (from > 2 weeks after symptom onset). In order to monitor the distribution of changes in the lungs more accurately, bilateral lungs were divided into 12 ‘lung’ zones. Each zone was assigned a CT score. Total severity score was calculated by summing the scores for each zone. Results. In 93.6% patients with COVID-19, the CT findings were positive. About 92.1% patients had multiple lesions. The lesions were bilateral in 87.6% of patients, localized both peripheral and centrally in 63.3% of patients, and occurred more frequently in posterior areas (93%), as well as in lower lung zones (91.2%). The average total severity score was 11.00 (7.00–16.00). The most common CT findings in all patients were the ground-glass opacities (97.7%), reticular pattern (91.3%), consolidation (71.5%) and fibrotic streaks (63.8%). In the group 1, changes on CT were found in 80.0%, in the group 2 in 95.0%, and in the group 3 in 99.4% of the patients. Conclusion. CT is proven to be a very important diagnostic method in COVID-19 patients, and together with clinical and laboratory findings, gives a complete picture of the patient's condition and contributes significantly to decision-making for further treatment. |
| format | Article |
| id | doaj-art-2c267e6cf9a74f0a85d13b5d360cc49f |
| institution | Kabale University |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-2c267e6cf9a74f0a85d13b5d360cc49f2025-08-20T03:55:17ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202021-01-0178664265010.2298/VSP200725125K0042-84502000125KCT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in SerbiaKosanović Tijana0Mišović Miroslav1https://orcid.org/0000-0002-4803-3341Đukić Vladimir2Lalošević Miodrag3https://orcid.org/0000-0002-1710-6114Đorđević Marjana4Rančić Nemanja5https://orcid.org/0000-0002-5122-8094University Hospital „Dr Dragiša Mišović – Dedinje“, Department of Radiology, Belgrade, Serbia University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia + Military Medical Academy, Institute of Radiology, Belgrade, Serbia University Hospital „Dr Dragiša Mišović – Dedinje“, Department of Radiology, Belgrade, SerbiaUniversity Hospital „Dr Dragiša Mišović – Dedinje“, Department of Radiology, Belgrade, SerbiaUniversity Hospital „Dr Dragiša Mišović – Dedinje“, Department of Radiology, Belgrade, SerbiaUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia + Military Medical Academy, Center for Clinical Pharmacology, Belgrade, Serbia Background/Aim. The corona virus disease 2019 (COVID-19) primarily affects the respiratory system, so radiological diagnosis has been shown to be necessary. Chest computed tomography (CT) is to be shown the best modality in suspected COVID-19 cases for initial evaluation because CT findings may be present before the onset of symptoms. The aim of this study was to show different CT imaging features or patterns in COVID-19 patients with a different time course and disease severity. Methods. This prospective cohort study analysed 330 patients (the average age was 52.37 ± 15.36) with confirmed COVID-19 via laboratory testing. During hospitalization, all patients included in the study underwent chest CT in order to assess the extent of changes in their lungs. COVID-19 patients, with a different time course and disease severity, were classified into four categories: lung, bronchial, pleural and mediastinal changes. Based on the time interval between the onset of symptoms and performed CT scan, all patients were divided into three groups: group 1 (CT scans done ≤ 1 week after symptom onset); group 2 (from > 1 to 2 weeks after symptom onset); group 3 (from > 2 weeks after symptom onset). In order to monitor the distribution of changes in the lungs more accurately, bilateral lungs were divided into 12 ‘lung’ zones. Each zone was assigned a CT score. Total severity score was calculated by summing the scores for each zone. Results. In 93.6% patients with COVID-19, the CT findings were positive. About 92.1% patients had multiple lesions. The lesions were bilateral in 87.6% of patients, localized both peripheral and centrally in 63.3% of patients, and occurred more frequently in posterior areas (93%), as well as in lower lung zones (91.2%). The average total severity score was 11.00 (7.00–16.00). The most common CT findings in all patients were the ground-glass opacities (97.7%), reticular pattern (91.3%), consolidation (71.5%) and fibrotic streaks (63.8%). In the group 1, changes on CT were found in 80.0%, in the group 2 in 95.0%, and in the group 3 in 99.4% of the patients. Conclusion. CT is proven to be a very important diagnostic method in COVID-19 patients, and together with clinical and laboratory findings, gives a complete picture of the patient's condition and contributes significantly to decision-making for further treatment.http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84502000125K.pdfcovid-19lungdiagnosisorgan dysfunction scorespneumoniaseverity of illness indextomography, x-ray computed |
| spellingShingle | Kosanović Tijana Mišović Miroslav Đukić Vladimir Lalošević Miodrag Đorđević Marjana Rančić Nemanja CT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in Serbia Vojnosanitetski Pregled covid-19 lung diagnosis organ dysfunction scores pneumonia severity of illness index tomography, x-ray computed |
| title | CT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in Serbia |
| title_full | CT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in Serbia |
| title_fullStr | CT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in Serbia |
| title_full_unstemmed | CT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in Serbia |
| title_short | CT appearance in the 330 patients with coronavirus disease 2019 (COVID-19) in Serbia |
| title_sort | ct appearance in the 330 patients with coronavirus disease 2019 covid 19 in serbia |
| topic | covid-19 lung diagnosis organ dysfunction scores pneumonia severity of illness index tomography, x-ray computed |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84502000125K.pdf |
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