GENOMIC FACTORS (TOLL-LIKE RECEPTORS GENES) IN DEVELOPMENT OF ATHEROSCLEROSIS AND ITS CLINICAL MANIFESTATIONS

GENOMIC FACTORS (TOLL-LIKE RECEPTORS GENES) IN DEVELOPMENT OF ATHEROSCLEROSIS AND ITS CLINICAL MANIFESTATIONS

Development of atherosclerosis and its clinical manifestations, i.e. unstable angina, myocardial infarction, and ischemic stroke, is largely determined by a genetic inheritance, particularly inherited variation of the genes encoding Toll-like receptors (TLRs), a major effector of innate immune syste...

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Bibliographic Details
Main Authors: I. I. Zhidkova, A. V. Ponasenko, M. V. Khutornaya, A. G. Kutikhin, O. L. Barbarash
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2017-07-01
Series:Медицинская иммунология
Subjects:
atherosclerosis
gene polymorphisms
toll-like receptors
allelic variants
innate immune receptors
inflammation
immune response
Online Access:https://www.mimmun.ru/mimmun/article/view/1258
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