High-Dose Antibiotics in Intensive Care: A Review of Their Role in Combatting and Contributing to Antimicrobial Resistance

High-Dose Antibiotics in Intensive Care: A Review of Their Role in Combatting and Contributing to Antimicrobial Resistance

Introduction. High-dose antibiotic regimens are commonly employed to improve outcomes in critically ill patients with severe infections; however, their direct impact on antimicrobial resistance (AMR) remains underexplored. Methods. This systematic review analyzed randomized controlled trials (RCTs)...

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Bibliographic Details
Main Authors: Galo G. Farfán-Cano, Carlos R. Cedeño-Cevallos
Format: Article
Language:English
Published: Universidad Nacional Hermilio Valdizán de Huánuco 2024-12-01
Series:Microbes, Infection and Chemotherapy
Subjects:
antimicrobial resistance
high-dose antibiotics
randomized controlled trials
gram-negative infections
Online Access:https://revistas.unheval.edu.pe/index.php/mic/article/view/2250
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