Kidney transplant outcomes in HLA desensitized patients with pretransplant CDC and/or FCM positive crossmatches

Kidney transplant outcomes in HLA desensitized patients with pretransplant CDC and/or FCM positive crossmatches

BackgroundKidney transplant (KT) candidates with very high calculated panel reactive alloantibody (cPRA >95%) have limited chances to receive an HLA-matched transplant unless they undergo pretransplant desensitization.ObjectiveTo assess the efficacy of immunoadsorption (IA) in desensitizing p...

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Bibliographic Details
Main Authors: Johan Noble, Céline Dard, Diane Giovannini, Hamza Naciri Bennani, Pierre Fournier, Béatrice Bardy, Anne Bourdin, Farida Imerzoukene, Lionel Motte, Florian Terrec, Paolo Malvezzi, Thomas Jouve, Lionel Rostaing
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
HLA incompatible transplantation
kidney transplantation
immunoadsorption
positive CDC crossmatch
desensitization
cPRA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1612462/full
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