Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis

Green analytical chemistry is concerned with making analytical techniques more secure and environmentally friendly. A crucial aspect of this approach is the assessment of the greenness of analytical methods. Remdesivir, a SARS-CoV-2 nucleotide analog RNA polymerase inhibitor, has been authorized by...

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Main Authors: Aesha Bhalodia, Sonal Desai
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Green Analytical Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772577424000582
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author Aesha Bhalodia
Sonal Desai
author_facet Aesha Bhalodia
Sonal Desai
author_sort Aesha Bhalodia
collection DOAJ
description Green analytical chemistry is concerned with making analytical techniques more secure and environmentally friendly. A crucial aspect of this approach is the assessment of the greenness of analytical methods. Remdesivir, a SARS-CoV-2 nucleotide analog RNA polymerase inhibitor, has been authorized by USFDA as the initial course of therapy for hospitalized COVID-19 patients. The proposed study evaluates greenness of several reported chromatographic methods for estimation of Remdesivir using seven different tools namely ComplexGAPI, BAGI, AGREE, AGREEprep, AMGS, ChlorTox and RGBfast.
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institution Kabale University
issn 2772-5774
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publishDate 2024-12-01
publisher Elsevier
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series Green Analytical Chemistry
spelling doaj-art-2bd88b0fe26644d69540d1c0b99b1d022024-12-08T06:13:20ZengElsevierGreen Analytical Chemistry2772-57742024-12-0111100149Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysisAesha Bhalodia0Sonal Desai1Department of Pharmaceutical Quality Assurance, SSR College of Pharmacy, Sayli Road, Silvassa, UT of Dadra and Nagar Haveli 396 230, IndiaCorresponding author.; Department of Pharmaceutical Quality Assurance, SSR College of Pharmacy, Sayli Road, Silvassa, UT of Dadra and Nagar Haveli 396 230, IndiaGreen analytical chemistry is concerned with making analytical techniques more secure and environmentally friendly. A crucial aspect of this approach is the assessment of the greenness of analytical methods. Remdesivir, a SARS-CoV-2 nucleotide analog RNA polymerase inhibitor, has been authorized by USFDA as the initial course of therapy for hospitalized COVID-19 patients. The proposed study evaluates greenness of several reported chromatographic methods for estimation of Remdesivir using seven different tools namely ComplexGAPI, BAGI, AGREE, AGREEprep, AMGS, ChlorTox and RGBfast.http://www.sciencedirect.com/science/article/pii/S2772577424000582AGREEAGREEprepAMGSBAGIChlorToxComplexGAPI
spellingShingle Aesha Bhalodia
Sonal Desai
Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis
Green Analytical Chemistry
AGREE
AGREEprep
AMGS
BAGI
ChlorTox
ComplexGAPI
title Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis
title_full Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis
title_fullStr Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis
title_full_unstemmed Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis
title_short Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis
title_sort application of seven tools for evaluation of greenness of chromatographic methods for remdesivir analysis
topic AGREE
AGREEprep
AMGS
BAGI
ChlorTox
ComplexGAPI
url http://www.sciencedirect.com/science/article/pii/S2772577424000582
work_keys_str_mv AT aeshabhalodia applicationofseventoolsforevaluationofgreennessofchromatographicmethodsforremdesiviranalysis
AT sonaldesai applicationofseventoolsforevaluationofgreennessofchromatographicmethodsforremdesiviranalysis