Effect of virulent and vaccine variants of influenza virus on the immunophenotype of dendritic cells generated from murine bone marrow

Effect of virulent and vaccine variants of influenza virus on the immunophenotype of dendritic cells generated from murine bone marrow

The aim of this study was to generate dendritic cells from the bone marrow of mice (DC) in vitro and to assess the effect of virulent and attenuated variants of influenza virus on the maturation of DCs. Granulocyte-macrophage colony stimulating factor (GM-CSF) and interleukin-4 (IL-4) were used in c...

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Bibliographic Details
Main Authors: N. K. Akhmatova, A. A. Rtishchev, S. G. Markushin, A. M. Kostinova, E. A. Akhmatova, V. N. Stolpnikova, E. O. Kalinichenko, I. Zh. Shubina, I. A. Bisheva
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2020-05-01
Series:Медицинская иммунология
Subjects:
cell culture
dendritic cells
morphology
influenza virus
virulent and attenuated variants
differentiation markers
toll-like receptors
Online Access:https://www.mimmun.ru/mimmun/article/view/1869
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