The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia species
Warburgia ugandensis, which is one of the indigenous species of Ethiopia, is known for its wide range of biological activities. A series of drimane sesquiterpenoids have been isolated from the stem bark of the plant. However, there is no report on the herbicidal potential of the plant against invasi...
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International Journal of Secondary Metabolite
2024-11-01
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| Series: | International Journal of Secondary Metabolite |
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| author | Christopher Suh Zelalem Gizachew |
| author_facet | Christopher Suh Zelalem Gizachew |
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| description | Warburgia ugandensis, which is one of the indigenous species of Ethiopia, is known for its wide range of biological activities. A series of drimane sesquiterpenoids have been isolated from the stem bark of the plant. However, there is no report on the herbicidal potential of the plant against invasive weeds like Parthenium hysterophorus. In this study, the herbicidal potential of W. ugandensis against the P. hysterophorus weed was investigated. Following the bioassay protocol, muzigadial as powerful phytotoxic compound together with other eight compounds were isolated from the EtOAc soluble portion of the ethanol extract of the bark of the plant. These compounds were identified using different physical and spectroscopic methods. The isolated compounds are albicanyl acetate (35), caseamemin (36), β-sitosterol (37), muzigadial (38), cinnamolide-3β-acetate (39), ugandensidial (40), 11α-hydroxy muzigadiolide (41), polygodial (42) and 9-deoxymuzigadial (43). The first three compounds are new to the species W. ugandensis. Furthermore, two other compounds namely heptacosanol (44) and hentriacontane (45) were also isolated from this species. In summary, the purpose of this study, to the best of my knowledge, is to provide the three initially identified compounds from the plant material and provide information on the plant's potential utility in agricultural applications. |
| format | Article |
| id | doaj-art-2b7a5c6e4e8846988f045ee1a6730ef2 |
| institution | Kabale University |
| issn | 2148-6905 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | International Journal of Secondary Metabolite |
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| series | International Journal of Secondary Metabolite |
| spelling | doaj-art-2b7a5c6e4e8846988f045ee1a6730ef22024-12-06T09:58:39ZengInternational Journal of Secondary MetaboliteInternational Journal of Secondary Metabolite2148-69052024-11-0111471072110.21448/ijsm.1404324618The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia speciesChristopher Suh0https://orcid.org/0000-0002-1141-2719Zelalem Gizachew1https://orcid.org/0000-0002-2504-4347Technologies for African Agricultural Transformation (TAAT),Bio and Emerging Technology InstituteWarburgia ugandensis, which is one of the indigenous species of Ethiopia, is known for its wide range of biological activities. A series of drimane sesquiterpenoids have been isolated from the stem bark of the plant. However, there is no report on the herbicidal potential of the plant against invasive weeds like Parthenium hysterophorus. In this study, the herbicidal potential of W. ugandensis against the P. hysterophorus weed was investigated. Following the bioassay protocol, muzigadial as powerful phytotoxic compound together with other eight compounds were isolated from the EtOAc soluble portion of the ethanol extract of the bark of the plant. These compounds were identified using different physical and spectroscopic methods. The isolated compounds are albicanyl acetate (35), caseamemin (36), β-sitosterol (37), muzigadial (38), cinnamolide-3β-acetate (39), ugandensidial (40), 11α-hydroxy muzigadiolide (41), polygodial (42) and 9-deoxymuzigadial (43). The first three compounds are new to the species W. ugandensis. Furthermore, two other compounds namely heptacosanol (44) and hentriacontane (45) were also isolated from this species. In summary, the purpose of this study, to the best of my knowledge, is to provide the three initially identified compounds from the plant material and provide information on the plant's potential utility in agricultural applications.https://dergipark.org.tr/en/download/article-file/3597086warburgia ugandensisalbicanyl acetatecaseameminisolationphytotoxic activitywarburgia ugandensisalbicanyl acetatecaseameminisolationphytotoxic activity |
| spellingShingle | Christopher Suh Zelalem Gizachew The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia species International Journal of Secondary Metabolite warburgia ugandensis albicanyl acetate caseamemin isolation phytotoxic activity warburgia ugandensis albicanyl acetate caseamemin isolation phytotoxic activity |
| title | The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia species |
| title_full | The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia species |
| title_fullStr | The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia species |
| title_full_unstemmed | The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia species |
| title_short | The isolation of bioactive compounds from Warburgia ugandensis bark: A report of albicanyl acetate, caseamemin and β-sitosterol from Warburgia species |
| title_sort | isolation of bioactive compounds from warburgia ugandensis bark a report of albicanyl acetate caseamemin and β sitosterol from warburgia species |
| topic | warburgia ugandensis albicanyl acetate caseamemin isolation phytotoxic activity warburgia ugandensis albicanyl acetate caseamemin isolation phytotoxic activity |
| url | https://dergipark.org.tr/en/download/article-file/3597086 |
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