Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
With the objective of finding new classes of cognitive enhancers with potential for the treatment of neurodegenerative disorders, such as Alzheimer's disease, small molecule inhibitors of insulin-regulated aminopeptidase (IRAP) were designed and synthesized. IRAP is a member of the M1 family of...
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| Main Authors: | Julia Beveridge, Marcus Söderström, Rubén Prieto-Díaz, Hugo Gutierrez-de-Teran, Luke R. Odell, Mathias Hallberg, Mats Larhed, Johan Gising |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | European Journal of Medicinal Chemistry Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417424000876 |
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