DRESSed for distress: a case of allopurinol-induced DRESS syndrome
DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) syndrome is a severe systemic drug reaction characterized by a latent period of several weeks following the initiation of drug therapy. Among the most well-known causative agents is allopurinol, commonly prescribed for managing asymptomat...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pensoft Publishers
2024-12-01
|
| Series: | Folia Medica |
| Online Access: | https://foliamedica.bg/article/126615/download/pdf/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841556481599602688 |
|---|---|
| author | Areti Kalfoutzou Aikaterini Doumana Aimilia-Iris Karamolegkou Adam Mylonakis Christos Piperis Maria Dimitrakoudi Eleni Mostratou |
| author_facet | Areti Kalfoutzou Aikaterini Doumana Aimilia-Iris Karamolegkou Adam Mylonakis Christos Piperis Maria Dimitrakoudi Eleni Mostratou |
| author_sort | Areti Kalfoutzou |
| collection | DOAJ |
| description | DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) syndrome is a severe systemic drug reaction characterized by a latent period of several weeks following the initiation of drug therapy. Among the most well-known causative agents is allopurinol, commonly prescribed for managing asymptomatic gout. Allopurinol-induced DRESS syndrome is associated with high mortality rates and significant long-term sequelae. This report details the case of an elderly female patient who presented with an extensive rash covering her trunk and extremities which was concurrent with her use of allopurinol. The condition progressed to renal impairment but showed significant improvement upon cessation of the drug and administration of high-dose corticosteroids. This case aims to shed light on one of the most underrecognized types of systemic drug reactions, hoping to raise awareness about this rare yet serious complication of one of the most widely prescribed drugs. |
| format | Article |
| id | doaj-art-2b0cb64c6ef14f1ea3f83682c19ac682 |
| institution | Kabale University |
| issn | 1314-2143 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Folia Medica |
| spelling | doaj-art-2b0cb64c6ef14f1ea3f83682c19ac6822025-01-07T08:30:13ZengPensoft PublishersFolia Medica1314-21432024-12-0166692993410.3897/folmed.66.e126615126615DRESSed for distress: a case of allopurinol-induced DRESS syndromeAreti Kalfoutzou0Aikaterini Doumana1Aimilia-Iris Karamolegkou2Adam Mylonakis3Christos Piperis4Maria Dimitrakoudi5Eleni Mostratou6251 Air Force General Hospital251 Air Force General Hospital251 Air Force General HospitalLaikon General HospitalGeorgios Gennimatas General HospitalLaikon General Hospital251 Air Force General HospitalDRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) syndrome is a severe systemic drug reaction characterized by a latent period of several weeks following the initiation of drug therapy. Among the most well-known causative agents is allopurinol, commonly prescribed for managing asymptomatic gout. Allopurinol-induced DRESS syndrome is associated with high mortality rates and significant long-term sequelae. This report details the case of an elderly female patient who presented with an extensive rash covering her trunk and extremities which was concurrent with her use of allopurinol. The condition progressed to renal impairment but showed significant improvement upon cessation of the drug and administration of high-dose corticosteroids. This case aims to shed light on one of the most underrecognized types of systemic drug reactions, hoping to raise awareness about this rare yet serious complication of one of the most widely prescribed drugs.https://foliamedica.bg/article/126615/download/pdf/ |
| spellingShingle | Areti Kalfoutzou Aikaterini Doumana Aimilia-Iris Karamolegkou Adam Mylonakis Christos Piperis Maria Dimitrakoudi Eleni Mostratou DRESSed for distress: a case of allopurinol-induced DRESS syndrome Folia Medica |
| title | DRESSed for distress: a case of allopurinol-induced DRESS syndrome |
| title_full | DRESSed for distress: a case of allopurinol-induced DRESS syndrome |
| title_fullStr | DRESSed for distress: a case of allopurinol-induced DRESS syndrome |
| title_full_unstemmed | DRESSed for distress: a case of allopurinol-induced DRESS syndrome |
| title_short | DRESSed for distress: a case of allopurinol-induced DRESS syndrome |
| title_sort | dressed for distress a case of allopurinol induced dress syndrome |
| url | https://foliamedica.bg/article/126615/download/pdf/ |
| work_keys_str_mv | AT aretikalfoutzou dressedfordistressacaseofallopurinolinduceddresssyndrome AT aikaterinidoumana dressedfordistressacaseofallopurinolinduceddresssyndrome AT aimiliairiskaramolegkou dressedfordistressacaseofallopurinolinduceddresssyndrome AT adammylonakis dressedfordistressacaseofallopurinolinduceddresssyndrome AT christospiperis dressedfordistressacaseofallopurinolinduceddresssyndrome AT mariadimitrakoudi dressedfordistressacaseofallopurinolinduceddresssyndrome AT elenimostratou dressedfordistressacaseofallopurinolinduceddresssyndrome |