Endovascular treatment of lower limb acute DVT: current trends and future directions
Abstract Aim of the study This systematic review aims to evaluate the efficacy, safety, and comparative outcomes of endovascular treatments for acute lower limb deep vein thrombosis (DVT), including catheter-directed thrombolysis (CDT), pharmacomechanical thrombectomy (PMT), mechanical thrombectomy,...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2024-11-01
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| Series: | CVIR Endovascular |
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| Online Access: | https://doi.org/10.1186/s42155-024-00495-x |
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| author | Francesco Siciliano Edoardo Ronconi Tommaso Rossi Federica Fanelli Miltiadis Krokidis Pasqualino Sirignano Michele Rossi Marcello Andrea Tipaldi |
| author_facet | Francesco Siciliano Edoardo Ronconi Tommaso Rossi Federica Fanelli Miltiadis Krokidis Pasqualino Sirignano Michele Rossi Marcello Andrea Tipaldi |
| author_sort | Francesco Siciliano |
| collection | DOAJ |
| description | Abstract Aim of the study This systematic review aims to evaluate the efficacy, safety, and comparative outcomes of endovascular treatments for acute lower limb deep vein thrombosis (DVT), including catheter-directed thrombolysis (CDT), pharmacomechanical thrombectomy (PMT), mechanical thrombectomy, and venous stenting, drawing insights from a diverse range of studies. Materials and methods A comprehensive literature search identified 33 relevant studies, including randomized controlled trials, cohort studies, systematic reviews, and case reports. Data extraction focused on study design, intervention type, outcome measures, and follow-up duration. Results Catheter-directed thrombolysis demonstrates promising results in enhancing venous patency and reducing post-thrombotic syndrome, with careful patient selection being crucial. Pharmacomechanical and mechanical thrombectomy devices offer immediate and long-term benefits, emphasizing individualized patient care. Venous stenting serves as a crucial adjunctive therapy, particularly in cases of residual venous obstruction, though further research is needed for optimal patient selection and long-term outcomes. Timing and selection of endovascular interventions remain critical considerations, necessitating multidisciplinary approaches and ongoing research. Conclusion This review provides valuable insights for clinicians and researchers, guiding evidence-based decision-making and shaping future research directions in the dynamic field of endovascular interventions for acute lower limb DVT. |
| format | Article |
| id | doaj-art-2ad0f1ea70a64b87aa8ee2a6d292827e |
| institution | Kabale University |
| issn | 2520-8934 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | CVIR Endovascular |
| spelling | doaj-art-2ad0f1ea70a64b87aa8ee2a6d292827e2024-12-01T12:46:31ZengSpringerOpenCVIR Endovascular2520-89342024-11-017111610.1186/s42155-024-00495-xEndovascular treatment of lower limb acute DVT: current trends and future directionsFrancesco Siciliano0Edoardo Ronconi1Tommaso Rossi2Federica Fanelli3Miltiadis Krokidis4Pasqualino Sirignano5Michele Rossi6Marcello Andrea Tipaldi7Department of Surgical and Medical Sciences and Translational Medicine School of Medicine and Psychology, “Sapienza” - University of RomeDepartment of Radiology, Sant’Andrea University Hospital La SapienzaDepartment of Radiological Sciences, Oncology and Pathology, Policlinico Umberto I Hospital, Sapienza University of RomeDepartment of Surgical and Medical Sciences and Translational Medicine School of Medicine and Psychology, “Sapienza” - University of RomeSchool of Medicine, National and Kapodistrian University of Athens Areteion Hospital Vascular and Endovascular Surgery Unit, Sant’Andrea Hospital of Rome, Department of General and Specialistic Surgery, “Sapienza” University of RomeDepartment of Surgical and Medical Sciences and Translational Medicine School of Medicine and Psychology, “Sapienza” - University of RomeDepartment of Surgical and Medical Sciences and Translational Medicine School of Medicine and Psychology, “Sapienza” - University of RomeAbstract Aim of the study This systematic review aims to evaluate the efficacy, safety, and comparative outcomes of endovascular treatments for acute lower limb deep vein thrombosis (DVT), including catheter-directed thrombolysis (CDT), pharmacomechanical thrombectomy (PMT), mechanical thrombectomy, and venous stenting, drawing insights from a diverse range of studies. Materials and methods A comprehensive literature search identified 33 relevant studies, including randomized controlled trials, cohort studies, systematic reviews, and case reports. Data extraction focused on study design, intervention type, outcome measures, and follow-up duration. Results Catheter-directed thrombolysis demonstrates promising results in enhancing venous patency and reducing post-thrombotic syndrome, with careful patient selection being crucial. Pharmacomechanical and mechanical thrombectomy devices offer immediate and long-term benefits, emphasizing individualized patient care. Venous stenting serves as a crucial adjunctive therapy, particularly in cases of residual venous obstruction, though further research is needed for optimal patient selection and long-term outcomes. Timing and selection of endovascular interventions remain critical considerations, necessitating multidisciplinary approaches and ongoing research. Conclusion This review provides valuable insights for clinicians and researchers, guiding evidence-based decision-making and shaping future research directions in the dynamic field of endovascular interventions for acute lower limb DVT.https://doi.org/10.1186/s42155-024-00495-xAcute vein thrombosisDeep vein thrombosisEndovascular thrombus removalCatheter-directed thrombolysis |
| spellingShingle | Francesco Siciliano Edoardo Ronconi Tommaso Rossi Federica Fanelli Miltiadis Krokidis Pasqualino Sirignano Michele Rossi Marcello Andrea Tipaldi Endovascular treatment of lower limb acute DVT: current trends and future directions CVIR Endovascular Acute vein thrombosis Deep vein thrombosis Endovascular thrombus removal Catheter-directed thrombolysis |
| title | Endovascular treatment of lower limb acute DVT: current trends and future directions |
| title_full | Endovascular treatment of lower limb acute DVT: current trends and future directions |
| title_fullStr | Endovascular treatment of lower limb acute DVT: current trends and future directions |
| title_full_unstemmed | Endovascular treatment of lower limb acute DVT: current trends and future directions |
| title_short | Endovascular treatment of lower limb acute DVT: current trends and future directions |
| title_sort | endovascular treatment of lower limb acute dvt current trends and future directions |
| topic | Acute vein thrombosis Deep vein thrombosis Endovascular thrombus removal Catheter-directed thrombolysis |
| url | https://doi.org/10.1186/s42155-024-00495-x |
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