Approaches to anticancer therapy based on modulation of DNA methylation

Approaches to anticancer therapy based on modulation of DNA methylation

Background. DNA methylation is a crucial mechanism of epigenetic regulation of transcription. Disturbances in DNA methylation mechanism are associated with various malignancies such as acute myeloid leukaemia, breast cancer, prostate cancer, etc. Influencing the functional status of DNA methyltransf...

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Bibliographic Details
Main Authors: V. P. Maksimova, J. V. Makus, V. G. Popova, O. G. Usalka, G. A. Belitsky, M. G. Yakubovskaya, K. I. Kirsanov
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2024-09-01
Series:Сибирский онкологический журнал
Subjects:
antitumour therapy
dna methylation
dnmts inhibitors
tets inhibitors
clinical trials
Online Access:https://www.siboncoj.ru/jour/article/view/3199
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https://www.siboncoj.ru/jour/article/view/3199

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