Clinical improvement, toxicity and future prospects of β-sitosterol: a review

β-sitosterol is waxy substance, white in color distributed in a variety of natural plant sources cereals, pulses, legumes, vegetables, fruits, and herbs. Several clinical and preclinical investigations indicate that β-sitosterol has a wide range of important health advantages. It prevents many types...

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Main Authors: Azka Khan Durrani, Momina Khalid, Awais Raza, Izza Faiz ul Rasool, Waseem Khalid, Muhammad Nadeem Akhtar, Ammar Ahmad Khan, Zunair Abdullah, Babirye Khadijah
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:CyTA - Journal of Food
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2024.2337886
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author Azka Khan Durrani
Momina Khalid
Awais Raza
Izza Faiz ul Rasool
Waseem Khalid
Muhammad Nadeem Akhtar
Ammar Ahmad Khan
Zunair Abdullah
Babirye Khadijah
author_facet Azka Khan Durrani
Momina Khalid
Awais Raza
Izza Faiz ul Rasool
Waseem Khalid
Muhammad Nadeem Akhtar
Ammar Ahmad Khan
Zunair Abdullah
Babirye Khadijah
author_sort Azka Khan Durrani
collection DOAJ
description β-sitosterol is waxy substance, white in color distributed in a variety of natural plant sources cereals, pulses, legumes, vegetables, fruits, and herbs. Several clinical and preclinical investigations indicate that β-sitosterol has a wide range of important health advantages. It prevents many types of malignancies, lowers levels of low density lipoprotein (LDL), lowers the risk of coronary artery disease, heart attacks, and atherosclerosis, and supports the body’s natural healing process. It is found to have cancer-protective properties and has the potency to be beneficial against breast, prostate, colon, lung, stomach, and leukemia. The present review provides a complete analysis and examines the literature on β-sitosterol from different dietary sources, with a focus on its toxicological characteristics and nutraceutical qualities. It lays down the theoretical basis and justification for directing the future planning and execution of clinical studies intended to confirm the importance and possible toxicity of β-sitosterol.
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institution Kabale University
issn 1947-6337
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language English
publishDate 2024-12-01
publisher Taylor & Francis Group
record_format Article
series CyTA - Journal of Food
spelling doaj-art-2ab97f09d84d4afe9d0875cb4992cdb72024-12-18T13:34:52ZengTaylor & Francis GroupCyTA - Journal of Food1947-63371947-63452024-12-0122110.1080/19476337.2024.2337886Clinical improvement, toxicity and future prospects of β-sitosterol: a reviewAzka Khan Durrani0Momina Khalid1Awais Raza2Izza Faiz ul Rasool3Waseem Khalid4Muhammad Nadeem Akhtar5Ammar Ahmad Khan6Zunair Abdullah7Babirye Khadijah8Faculty of Allied Health Sciences, University Institute of Food Science and Technology, The University of Lahore, Lahore, PakistanDepartment of Food Science, Government College University Faisalabad, Faisalabad, PakistanFaculty of Allied Health Sciences, University Institute of Food Science and Technology, The University of Lahore, Lahore, PakistanDepartment of Food Science, Government College University Faisalabad, Faisalabad, PakistanFaculty of Allied Health Sciences, University Institute of Food Science and Technology, The University of Lahore, Lahore, PakistanFaculty of Allied Health Sciences, University Institute of Diet and Nutritional Sciences, The University of Lahore, Lahore, PakistanFaculty of Allied Health Sciences, University Institute of Food Science and Technology, The University of Lahore, Lahore, PakistanFaculty of Allied Health Sciences, University Institute of Food Science and Technology, The University of Lahore, Lahore, PakistanDepartment of Food Science and Nutrition, Islamic University in Uganda, Mbale, Ugandaβ-sitosterol is waxy substance, white in color distributed in a variety of natural plant sources cereals, pulses, legumes, vegetables, fruits, and herbs. Several clinical and preclinical investigations indicate that β-sitosterol has a wide range of important health advantages. It prevents many types of malignancies, lowers levels of low density lipoprotein (LDL), lowers the risk of coronary artery disease, heart attacks, and atherosclerosis, and supports the body’s natural healing process. It is found to have cancer-protective properties and has the potency to be beneficial against breast, prostate, colon, lung, stomach, and leukemia. The present review provides a complete analysis and examines the literature on β-sitosterol from different dietary sources, with a focus on its toxicological characteristics and nutraceutical qualities. It lays down the theoretical basis and justification for directing the future planning and execution of clinical studies intended to confirm the importance and possible toxicity of β-sitosterol.https://www.tandfonline.com/doi/10.1080/19476337.2024.2337886Phytosterolsstanol estersdeoxyxylulose and mevalonate pathwaylow density lipoprotein (LDL)coronary artery disease
spellingShingle Azka Khan Durrani
Momina Khalid
Awais Raza
Izza Faiz ul Rasool
Waseem Khalid
Muhammad Nadeem Akhtar
Ammar Ahmad Khan
Zunair Abdullah
Babirye Khadijah
Clinical improvement, toxicity and future prospects of β-sitosterol: a review
CyTA - Journal of Food
Phytosterols
stanol esters
deoxyxylulose and mevalonate pathway
low density lipoprotein (LDL)
coronary artery disease
title Clinical improvement, toxicity and future prospects of β-sitosterol: a review
title_full Clinical improvement, toxicity and future prospects of β-sitosterol: a review
title_fullStr Clinical improvement, toxicity and future prospects of β-sitosterol: a review
title_full_unstemmed Clinical improvement, toxicity and future prospects of β-sitosterol: a review
title_short Clinical improvement, toxicity and future prospects of β-sitosterol: a review
title_sort clinical improvement toxicity and future prospects of β sitosterol a review
topic Phytosterols
stanol esters
deoxyxylulose and mevalonate pathway
low density lipoprotein (LDL)
coronary artery disease
url https://www.tandfonline.com/doi/10.1080/19476337.2024.2337886
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