GSH/pH-responsive copper-based cascade nanocomplexes inducing immunogenic cell death through cuproptosis/ferroptosis/necroptosis in oral squamous cell carcinoma

GSH/pH-responsive copper-based cascade nanocomplexes inducing immunogenic cell death through cuproptosis/ferroptosis/necroptosis in oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) remains a formidable challenge due to high recurrence rates and limited efficacy of conventional treatments. Immunotherapy holds potential, but its effectiveness is often restricted by low patient responsiveness. This study presents a novel therapeutic strategy us...

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Bibliographic Details
Main Authors: Yi Sun, Enze Li, Wenzhao Zhong, Zhaoming Deng, Ziyao Zhou, Ka Hong Wong, Xiangwei Li
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Materials Today Bio
Subjects:
Oral squamous cell carcinomas
Cuproptosis
Ferroptosis
Necroptosis
Immunogenic cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004952
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