Enhancement of efferocytosis through biased FPR2 signaling attenuates intestinal inflammation

Enhancement of efferocytosis through biased FPR2 signaling attenuates intestinal inflammation

Abstract Efficient clearance of dying cells (efferocytosis) is an evolutionarily conserved process for tissue homeostasis. Genetic enhancement of efferocytosis exhibits therapeutic potential for inflammation resolution and tissue repair. However, pharmacological approaches to enhance efferocytosis r...

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Main Authors: Ming‐Yue Wu, Yun‐Jun Ge, Er‐Jin Wang, Qi‐Wen Liao, Zheng‐Yu Ren, Yang Yu, Guoyuan Zhu, Chun‐Ping Liu, Meng‐Ni Zhang, Huanxing Su, Han‐Ming Shen, Ye Chen, Lei Wang, Yi‐Tao Wang, Min Li, Zhaoxiang Bian, Jin Chai, Richard D Ye, Jia‐Hong Lu
Format: Article
Language:English
Published: Springer Nature 2023-11-01
Series:EMBO Molecular Medicine
Subjects:
columbamine
FPR2
inflammatory bowel disease
LC3‐associated efferocytosis
Online Access:https://doi.org/10.15252/emmm.202317815
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https://doi.org/10.15252/emmm.202317815

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