Regulatory T-cell depletion in the setting of autologous stem cell transplantation for multiple myeloma: pilot study

Background Progression after high-dose melphalan with autologous stem cell transplantation (ASCT) in multiple myeloma (MM) may be due in part to immune dysfunction. Regulatory T (Treg) cells reconstitute rapidly after ASCT and inhibit immune responses against myeloma cells.Methods We performed a ran...

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Bibliographic Details
Main Authors: Justin Kline, Yuanyuan Zha, Benjamin A Derman, Todd M Zimmerman, Rebecca Malloy, Andrzej Jakubowiak, Michael R Bishop
Format: Article
Language:English
Published: BMJ Publishing Group 2020-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000286.full
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