A suppression-modification gene drive for malaria control targeting the ultra-conserved RNA gene mir-184

A suppression-modification gene drive for malaria control targeting the ultra-conserved RNA gene mir-184

Abstract Gene drive technology presents a promising approach to controlling malaria vector populations. Suppression drives are intended to disrupt essential mosquito genes whereas modification drives aim to reduce the individual vectorial capacity of mosquitoes. Here we present a highly efficient ho...

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Main Authors: Sebald A. N. Verkuijl, Giuseppe Del Corsano, Paolo Capriotti, Pei-Shi Yen, Maria Grazia Inghilterra, Prashanth Selvaraj, Astrid Hoermann, Aida Martinez-Sanchez, Chiamaka Valerie Ukegbu, Temesgen M. Kebede, Dina Vlachou, George K. Christophides, Nikolai Windbichler
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58954-5
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