Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada
Introduction Urgent, tailored and equitable action is needed to address the alarming rise in syphilis rates in Canada. In the last decade, the rates of infectious syphilis have increased by 345% in Ontario, Canada. Underserved populations—people who use drugs, un(der)housed individuals and those liv...
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BMJ Publishing Group
2024-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/14/12/e089021.full |
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| author | Patrick O'Byrne Melissa Richard-Greenblatt Michael Evans Jennifer Adams Brad Stoner Patrick O’Byrne Sahar Saeed Vanessa Tran Lucy Mackrell Megan Carter Maggie Hoover Natasha Larkin Felicia Maria G Magpantay Sicheng Zhao Bradley Stoner Kira Mandryk Kandace Belanger Jennifer Burbidge Gilles Charette Gabrielle Deschenes Duy A Dinh Amanda Featherstone Farhan Khandakar Jorge Martinez-Cajas Nicole Szumlanski Stephanie Vance Jessica Burnside Clare Mak Erin Stienstra Patrick Sanderson Eric Geen Nancy McGeachy Stephanie McFaul Susan LaBrie Brooke Rasinho Christine Brannan Michelle Street Melanie St John Casey Cassan Sandra Dereski Taylor Labadie Mary France Lynn Leggett Caron-Bruneau |
| author_facet | Patrick O'Byrne Melissa Richard-Greenblatt Michael Evans Jennifer Adams Brad Stoner Patrick O’Byrne Sahar Saeed Vanessa Tran Lucy Mackrell Megan Carter Maggie Hoover Natasha Larkin Felicia Maria G Magpantay Sicheng Zhao Bradley Stoner Kira Mandryk Kandace Belanger Jennifer Burbidge Gilles Charette Gabrielle Deschenes Duy A Dinh Amanda Featherstone Farhan Khandakar Jorge Martinez-Cajas Nicole Szumlanski Stephanie Vance Jessica Burnside Clare Mak Erin Stienstra Patrick Sanderson Eric Geen Nancy McGeachy Stephanie McFaul Susan LaBrie Brooke Rasinho Christine Brannan Michelle Street Melanie St John Casey Cassan Sandra Dereski Taylor Labadie Mary France Lynn Leggett Caron-Bruneau |
| collection | DOAJ |
| description | Introduction Urgent, tailored and equitable action is needed to address the alarming rise in syphilis rates in Canada. In the last decade, the rates of infectious syphilis have increased by 345% in Ontario, Canada. Underserved populations—people who use drugs, un(der)housed individuals and those living in rural and remote areas—face unique social and healthcare challenges that increase their vulnerability to syphilis infections and hinder their access to timely diagnosis and treatment. This study assesses the real-world implementation and effectiveness of using a recently approved syphilis point-of-care test in conjunction with public health outreach to break barriers and bring services to the population at the highest risk.Methods and analysis The Syphilis Rapid Point-of-Care Testing and Immediate Treatment Evaluation (SPRITE) study includes eight public health units in Ontario, Canada. Implementation and evaluation of this rapid ‘test and treat’ outreach model of care will be assessed using the Practical, Robust Implementation and Sustainability Model (PRISM)/Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) Framework, following a community-based participatory approach. Network models will be used to estimate the population-level impact of implementing this model of care to curb transmission. Knowledge mobilisation will be assessed using the Reciprocity, Externalities, Access, and Partnership (REAP) Self-Assessment Model.Ethics and dissemination The SPRITE study was approved by the Queen’s University Research Ethics Board (REB) and is to be conducted in accordance with the Canadian Tri-Council Policy Statement V.2 and the latest Seoul revision of the Declaration of Helsinki. Knowledge generated from this study will be mobilised through community-based organisations and the broader public health community. |
| format | Article |
| id | doaj-art-29d7a1b94c5f4de7ba09cbde69973807 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-29d7a1b94c5f4de7ba09cbde699738072025-01-14T15:05:13ZengBMJ Publishing GroupBMJ Open2044-60552024-12-01141210.1136/bmjopen-2024-089021Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada Patrick O'Byrne0Melissa Richard-Greenblatt1Michael EvansJennifer AdamsBrad StonerPatrick O’ByrneSahar Saeed2Vanessa Tran3Lucy Mackrell4Megan Carter5Maggie Hoover6Natasha Larkin7Felicia Maria G Magpantay8Sicheng Zhao9Bradley Stoner10Kira Mandryk11Kandace Belanger12Jennifer Burbidge13Gilles Charette14Gabrielle Deschenes15Duy A Dinh16Amanda Featherstone17Farhan Khandakar18Jorge Martinez-Cajas19Nicole Szumlanski20Stephanie Vance21Jessica BurnsideClare MakErin StienstraPatrick SandersonEric GeenNancy McGeachyStephanie McFaulSusan LaBrieBrooke RasinhoChristine BrannanMichelle StreetMelanie St JohnCasey CassanSandra DereskiTaylor LabadieMary FranceLynn Leggett Caron-Bruneau5 Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada9 Public Health Ontario, Toronto, Ontario, Canada1 Department of Public Health Sciences, Queen`s University, Kingston, Ontario, Canada9 Public Health Ontario, Toronto, Ontario, Canada1 Department of Public Health Sciences, Queen`s University, Kingston, Ontario, Canada1 Department of Public Health Sciences, Queen`s University, Kingston, Ontario, Canada3 Queen`s University, Kingston, Ontario, Canada3 Queen`s University, Kingston, Ontario, Canada8 Department of Mathematics and Statistics, Queen`s University, Kingston, Ontario, Canada8 Department of Mathematics and Statistics, Queen`s University, Kingston, Ontario, Canada1 Department of Public Health Sciences, Queen`s University, Kingston, Ontario, Canada6 Ottawa Public Health, Ottawa, Ontario, Canada10 Thunder Bay District Health Unit, Thunder Bay, Ontario, Canada9 Public Health Ontario, Toronto, Ontario, Canada11 Trellis HIV and Community Care, Kingston, Ontario, Canada12 Leeds Grenville and Lanark District Health Unit, Brockville, Ontario, Canada13 Faculty of Health Sciences, Queen`s University, Kingston, Ontario, Canada1 Department of Public Health Sciences, Queen`s University, Kingston, Ontario, Canada1 Department of Public Health Sciences, Queen`s University, Kingston, Ontario, Canada3 Queen`s University, Kingston, Ontario, Canada4 Kingston Frontenac and Lennox and Addington Public Health, Kingston, Ontario, Canada16 Hastings Prince Edward Public Health, Belleville, Ontario, CanadaIntroduction Urgent, tailored and equitable action is needed to address the alarming rise in syphilis rates in Canada. In the last decade, the rates of infectious syphilis have increased by 345% in Ontario, Canada. Underserved populations—people who use drugs, un(der)housed individuals and those living in rural and remote areas—face unique social and healthcare challenges that increase their vulnerability to syphilis infections and hinder their access to timely diagnosis and treatment. This study assesses the real-world implementation and effectiveness of using a recently approved syphilis point-of-care test in conjunction with public health outreach to break barriers and bring services to the population at the highest risk.Methods and analysis The Syphilis Rapid Point-of-Care Testing and Immediate Treatment Evaluation (SPRITE) study includes eight public health units in Ontario, Canada. Implementation and evaluation of this rapid ‘test and treat’ outreach model of care will be assessed using the Practical, Robust Implementation and Sustainability Model (PRISM)/Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) Framework, following a community-based participatory approach. Network models will be used to estimate the population-level impact of implementing this model of care to curb transmission. Knowledge mobilisation will be assessed using the Reciprocity, Externalities, Access, and Partnership (REAP) Self-Assessment Model.Ethics and dissemination The SPRITE study was approved by the Queen’s University Research Ethics Board (REB) and is to be conducted in accordance with the Canadian Tri-Council Policy Statement V.2 and the latest Seoul revision of the Declaration of Helsinki. Knowledge generated from this study will be mobilised through community-based organisations and the broader public health community.https://bmjopen.bmj.com/content/14/12/e089021.full |
| spellingShingle | Patrick O'Byrne Melissa Richard-Greenblatt Michael Evans Jennifer Adams Brad Stoner Patrick O’Byrne Sahar Saeed Vanessa Tran Lucy Mackrell Megan Carter Maggie Hoover Natasha Larkin Felicia Maria G Magpantay Sicheng Zhao Bradley Stoner Kira Mandryk Kandace Belanger Jennifer Burbidge Gilles Charette Gabrielle Deschenes Duy A Dinh Amanda Featherstone Farhan Khandakar Jorge Martinez-Cajas Nicole Szumlanski Stephanie Vance Jessica Burnside Clare Mak Erin Stienstra Patrick Sanderson Eric Geen Nancy McGeachy Stephanie McFaul Susan LaBrie Brooke Rasinho Christine Brannan Michelle Street Melanie St John Casey Cassan Sandra Dereski Taylor Labadie Mary France Lynn Leggett Caron-Bruneau Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada BMJ Open |
| title | Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada |
| title_full | Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada |
| title_fullStr | Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada |
| title_full_unstemmed | Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada |
| title_short | Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study: a mixed-methods implementation science research protocol of eight public health units in Ontario, Canada |
| title_sort | syphilis point of care rapid test and immediate treatment evaluation sprite study a mixed methods implementation science research protocol of eight public health units in ontario canada |
| url | https://bmjopen.bmj.com/content/14/12/e089021.full |
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