Deferasirox improved iron homeostasis and hematopoiesis in ovariectomized rats with iron accumulation

Deferasirox improved iron homeostasis and hematopoiesis in ovariectomized rats with iron accumulation

Abstract Menopause is a natural biological aging process characterized by the loss of ovarian follicular function and decrease estrogen levels. These hormonal fluctuations are associated with increased iron levels, which ultimately lead to iron accumulation. This study aims to investigate the effect...

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Bibliographic Details
Main Authors: Niloofar Honari, Mahtab Sayadi, Seyed Mehdi Sajjadi, Somayeh Solhjoo, Gholamreza Anani Sarab
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Deferasirox
Hematopoiesis
Iron Homeostasis
Menopause
Ovariectomy
Oxidative stress
Online Access:https://doi.org/10.1038/s41598-025-86333-z
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