The Role of Activated Stromal Cells in Fibrotic Foci Formation and Reversion

The Role of Activated Stromal Cells in Fibrotic Foci Formation and Reversion

Fibrotic focus is a pivotal morphofunctional unit in developing fibrosis in various tissues. For most fibrotic diseases, including progressive forms, the foci are considered unable to remodel and contribute to the worsening of prognosis. Unfortunately, the dynamics of the fibrotic focus formation an...

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Main Authors: Nataliya Andreevna Basalova, Maksim Alexandrovich Vigovskiy, Vladimir Sergeevich Popov, Evgeniya Alexandrovna Lagereva, Olga Alexandrovna Grigorieva, Anastasia Yuryevna Efimenko
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
activated stromal cells
fibrosis
myofibroblasts
fibroblast activation protein
FAPα
CD90 (THY-1)
Online Access:https://www.mdpi.com/2073-4409/13/24/2064
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