Nicotine’s impact on platelet function: insights into hemostasis mechanisms

Nicotine’s impact on platelet function: insights into hemostasis mechanisms

IntroductionTraditional Miao and Dai Chinese medicines have used nicotine-rich leaf tobacco to treat traumatic injuries by promoting hemostasis. While nicotine is known to enhance platelet aggregation, its effects on other platelet functions and underlying mechanisms remain unclear.Methods and Resul...

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Bibliographic Details
Main Authors: Xiayu Wu, Yongjun Liu, Changhao Zou, Fuqin He, Fang Guo, Sijia Liu, Yi Fan, Xuedong Zhu, Qianyi Zhou, Dan Shu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
nicotine
platelets
thrombin
[Ca2+]i
PAR4 receptor pathway
αIIbβ3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1512142/full
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