Early release of circulating tumor cells after transarterial chemoembolization hinders therapeutic response in patients with hepatocellular carcinoma

Early release of circulating tumor cells after transarterial chemoembolization hinders therapeutic response in patients with hepatocellular carcinoma

Abstract Background Transarterial chemoembolization (TACE) is the first-line therapeutic option for patients with intermediate-stage hepatocellular carcinoma (HCC). Tumor neovascularization allows tumor growth and may facilitate the release of circulating tumor cells (CTCs) to the bloodstream after...

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Main Authors: María L. Espejo-Cruz, Sandra González-Rubio, Juan J. Espejo, Javier M. Zamora-Olaya, María Prieto-Torre, Clara I. Linares, Álvaro Ruiz-Ramas, Álvaro Jiménez-Arranz, Marta Guerrero-Misas, Pilar Barrera-Baena, Antonio Poyato-González, José L. Montero, Marina Sánchez-Frías, María D. Ayllón, Manuel L. Rodríguez-Perálvarez, Manuel de la Mata, Gustavo Ferrín
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
Hepatocellular carcinoma
Transarterial chemoembolization
Circulating tumor cells
Liquid biopsy
Predictive model
Online Access:https://doi.org/10.1186/s12967-025-06092-3
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