An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH

An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH

ABSTRACT The mechanisms controlling Mycobacterium tuberculosis (Mtb) replication and survival inside its human host remain ill-defined. Phagosome acidification and nutrient deprivation are common mechanisms used by macrophages to restrict the replication of intracellular bacteria. Mtb stops replicat...

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Bibliographic Details
Main Authors:	Claire Healy, Sabine Ehrt, Alexandre Gouzy
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-01-01
Series:	mBio
Subjects:	Mycobacterium tuberculosis inorganic phosphate acid stress glycerol carbon metabolism
Online Access:	https://journals.asm.org/doi/10.1128/mbio.02825-24
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