Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging Research
Perivascular adipose tissue, which constitutes perivascular components along with the adventitial vasa vasorum, plays an important role as a source of various inflammatory mediators in cardiovascular disease. Inflammatory changes in the coronary adventitia are thought to be involved in the pathogene...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2019-01-01
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| Series: | European Cardiology Review |
| Online Access: | https://www.ecrjournal.com/articles/coronary-artery-spasm-and-perivascular-adipose-tissue-inflammation-insights-translational |
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| _version_ | 1846122519567794176 |
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| author | Kazuma Ohyama Yasuharu Matsumoto Hiroaki Shimokawa |
| author_facet | Kazuma Ohyama Yasuharu Matsumoto Hiroaki Shimokawa |
| author_sort | Kazuma Ohyama |
| collection | DOAJ |
| description | Perivascular adipose tissue, which constitutes perivascular components along with the adventitial vasa vasorum, plays an important role as a source of various inflammatory mediators in cardiovascular disease. Inflammatory changes in the coronary adventitia are thought to be involved in the pathogenesis of coronary artery spasm and vasospastic angina. Recent advances in translational research using non- invasive imaging modalities, including 18F-fluorodeoxyglucose PET and cardiac CT, have enabled us to visualise perivascular inflammation in the pathogenesis of coronary artery spasm. These modality approaches appear to be clinically useful as a non-invasive tool for examining the presence and severity of vasospastic angina. |
| format | Article |
| id | doaj-art-2869d19f8f1a496daa29064aeb50617c |
| institution | Kabale University |
| issn | 1758-3756 1758-3764 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | European Cardiology Review |
| spelling | doaj-art-2869d19f8f1a496daa29064aeb50617c2024-12-14T16:01:09ZengRadcliffe Medical MediaEuropean Cardiology Review1758-37561758-37642019-01-011416910.15420/ecr.2019.3.2Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging ResearchKazuma Ohyama0Yasuharu Matsumoto1Hiroaki Shimokawa2Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, JapanDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, JapanDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, JapanPerivascular adipose tissue, which constitutes perivascular components along with the adventitial vasa vasorum, plays an important role as a source of various inflammatory mediators in cardiovascular disease. Inflammatory changes in the coronary adventitia are thought to be involved in the pathogenesis of coronary artery spasm and vasospastic angina. Recent advances in translational research using non- invasive imaging modalities, including 18F-fluorodeoxyglucose PET and cardiac CT, have enabled us to visualise perivascular inflammation in the pathogenesis of coronary artery spasm. These modality approaches appear to be clinically useful as a non-invasive tool for examining the presence and severity of vasospastic angina.https://www.ecrjournal.com/articles/coronary-artery-spasm-and-perivascular-adipose-tissue-inflammation-insights-translational |
| spellingShingle | Kazuma Ohyama Yasuharu Matsumoto Hiroaki Shimokawa Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging Research European Cardiology Review |
| title | Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging Research |
| title_full | Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging Research |
| title_fullStr | Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging Research |
| title_full_unstemmed | Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging Research |
| title_short | Coronary Artery Spasm and Perivascular Adipose Tissue Inflammation: Insights From Translational Imaging Research |
| title_sort | coronary artery spasm and perivascular adipose tissue inflammation insights from translational imaging research |
| url | https://www.ecrjournal.com/articles/coronary-artery-spasm-and-perivascular-adipose-tissue-inflammation-insights-translational |
| work_keys_str_mv | AT kazumaohyama coronaryarteryspasmandperivascularadiposetissueinflammationinsightsfromtranslationalimagingresearch AT yasuharumatsumoto coronaryarteryspasmandperivascularadiposetissueinflammationinsightsfromtranslationalimagingresearch AT hiroakishimokawa coronaryarteryspasmandperivascularadiposetissueinflammationinsightsfromtranslationalimagingresearch |