Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier Membranes

Objective This study has evaluated the applicability and microstructure of polymeric membranes produced by poly(vinyl alcohol) (PVA) and poly(lactic acid) (PLA) solutions developed through an airbrush pen by the Solution Blow Spinning (SBS) technique.Materials and Methods Polymeric solutions with di...

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Main Authors: Fabiano Luiz Heggendorn, Ellen dos Santos, Maria Eduarda Samora Viana, Pablo Lourenço Fernandes, Arthur Henrique Vidigal de Miranda, Paulo Henrique de Souza Picciani
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of the California Dental Association
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Online Access:https://www.tandfonline.com/doi/10.1080/19424396.2024.2386089
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author Fabiano Luiz Heggendorn
Ellen dos Santos
Maria Eduarda Samora Viana
Pablo Lourenço Fernandes
Arthur Henrique Vidigal de Miranda
Paulo Henrique de Souza Picciani
author_facet Fabiano Luiz Heggendorn
Ellen dos Santos
Maria Eduarda Samora Viana
Pablo Lourenço Fernandes
Arthur Henrique Vidigal de Miranda
Paulo Henrique de Souza Picciani
author_sort Fabiano Luiz Heggendorn
collection DOAJ
description Objective This study has evaluated the applicability and microstructure of polymeric membranes produced by poly(vinyl alcohol) (PVA) and poly(lactic acid) (PLA) solutions developed through an airbrush pen by the Solution Blow Spinning (SBS) technique.Materials and Methods Polymeric solutions with different concentrations were used: PLA 20%, PLA 25% and PLA 40% in CH3Cl, PLA 20% in 2,2,2-trifluoroethanol (PLA 20%/TFE), PVA 20%, PVA 25% and PVA 40% and 20% PVA with 10% microcrystalline cellulose (PVA 20%/MC 10%) in water. A commercial airbrush device were used to deposit the polymer membranes, with distances of 5 and 10 cm from the vitreous, aluminum and bone surfaces. Polymer coverage of areas of interest and bone defects were evaluated by optical microscopy, scanning electron microscopy (SEM) and 3D scanning.Results Only a distance of 10 cm between the tip and the collector produced homogeneous membranes under the experimental conditions. PLA solutions at PLA 20%, PLA 25% and PLA 20%/TFE formed polymeric membranes, while depositions of PVA 20%, PVA 25% and PVA 20%/MC 10% created adherent films on structures with the absence of fibrous structures on surfaces. PLA deposition ensured complete closure of bone defects.Conclusions The use of polymeric solutions, using the SBS technique, depositing membranes using an airbrush pen demonstrated the formation of membranes at concentrations of PLA 20%, PLA 25% and PLA 20%/TFE.Practical Implications The direct deposition of polymeric membranes at the surgical site may represent an advance in guided bone regeneration, allowing the dental surgeon autonomy in the deposition of barrier membranes.
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spelling doaj-art-2848efdad2d94903a3deab33d5eae4292024-12-20T15:13:58ZengTaylor & Francis GroupJournal of the California Dental Association1942-43962024-12-0152110.1080/19424396.2024.2386089Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier MembranesFabiano Luiz Heggendorn0Ellen dos Santos1Maria Eduarda Samora Viana2Pablo Lourenço Fernandes3Arthur Henrique Vidigal de Miranda4Paulo Henrique de Souza Picciani5Post-Graduate Program in Dentistry, Grande Rio University (UNIGRANRIO), Duque de Caxias, BrazilBiomaterials Laboratory, Faculty of Dentistry of Universidade do Grande Rio (UNIGRANRIO), Rua Prof. José de Souza Herdy, Duque de Caxias, BrazilBiomaterials Laboratory, Faculty of Dentistry of Universidade do Grande Rio (UNIGRANRIO), Rua Prof. José de Souza Herdy, Duque de Caxias, BrazilPost-Graduate Program in Dentistry, Grande Rio University (UNIGRANRIO), Duque de Caxias, BrazilBiomaterials Laboratory, IMA – Institute of Macromolecules Professor Eloisa Mano, Federal University of Rio de Janeiro – Av. Horácio Macedo, 2030. Technology Center, Rio de Janeiro, BrazilBiomaterials Laboratory, IMA – Institute of Macromolecules Professor Eloisa Mano, Federal University of Rio de Janeiro – Av. Horácio Macedo, 2030. Technology Center, Rio de Janeiro, BrazilObjective This study has evaluated the applicability and microstructure of polymeric membranes produced by poly(vinyl alcohol) (PVA) and poly(lactic acid) (PLA) solutions developed through an airbrush pen by the Solution Blow Spinning (SBS) technique.Materials and Methods Polymeric solutions with different concentrations were used: PLA 20%, PLA 25% and PLA 40% in CH3Cl, PLA 20% in 2,2,2-trifluoroethanol (PLA 20%/TFE), PVA 20%, PVA 25% and PVA 40% and 20% PVA with 10% microcrystalline cellulose (PVA 20%/MC 10%) in water. A commercial airbrush device were used to deposit the polymer membranes, with distances of 5 and 10 cm from the vitreous, aluminum and bone surfaces. Polymer coverage of areas of interest and bone defects were evaluated by optical microscopy, scanning electron microscopy (SEM) and 3D scanning.Results Only a distance of 10 cm between the tip and the collector produced homogeneous membranes under the experimental conditions. PLA solutions at PLA 20%, PLA 25% and PLA 20%/TFE formed polymeric membranes, while depositions of PVA 20%, PVA 25% and PVA 20%/MC 10% created adherent films on structures with the absence of fibrous structures on surfaces. PLA deposition ensured complete closure of bone defects.Conclusions The use of polymeric solutions, using the SBS technique, depositing membranes using an airbrush pen demonstrated the formation of membranes at concentrations of PLA 20%, PLA 25% and PLA 20%/TFE.Practical Implications The direct deposition of polymeric membranes at the surgical site may represent an advance in guided bone regeneration, allowing the dental surgeon autonomy in the deposition of barrier membranes.https://www.tandfonline.com/doi/10.1080/19424396.2024.2386089Aerographypolymersguided tissue regeneration
spellingShingle Fabiano Luiz Heggendorn
Ellen dos Santos
Maria Eduarda Samora Viana
Pablo Lourenço Fernandes
Arthur Henrique Vidigal de Miranda
Paulo Henrique de Souza Picciani
Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier Membranes
Journal of the California Dental Association
Aerography
polymers
guided tissue regeneration
title Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier Membranes
title_full Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier Membranes
title_fullStr Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier Membranes
title_full_unstemmed Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier Membranes
title_short Application of Solution Blow Spinning (SBS) Through Airbrush Pen for in situ Generation of Barrier Membranes
title_sort application of solution blow spinning sbs through airbrush pen for in situ generation of barrier membranes
topic Aerography
polymers
guided tissue regeneration
url https://www.tandfonline.com/doi/10.1080/19424396.2024.2386089
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