Integrated membranes system for water application in microbiology/molecular biology

Abstract An integrated membrane filtration system was developed to make water purity suitable for microbiology/molecular biology research. Water samples were collected from outlets in different buildings of the National Research Center and analyzed for their composition before filtration. An integra...

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Main Authors: Heba Abdallah, Dina Nadeem Abd-Elshafy, Marwa Shalaby, Kareem Awad, Rola Nadeem, Ahmed Shaban, Mahmoud Mohamed Bahgat
Format: Article
Language:English
Published: SpringerOpen 2024-10-01
Series:Applied Water Science
Subjects:
Online Access:https://doi.org/10.1007/s13201-024-02294-0
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author Heba Abdallah
Dina Nadeem Abd-Elshafy
Marwa Shalaby
Kareem Awad
Rola Nadeem
Ahmed Shaban
Mahmoud Mohamed Bahgat
author_facet Heba Abdallah
Dina Nadeem Abd-Elshafy
Marwa Shalaby
Kareem Awad
Rola Nadeem
Ahmed Shaban
Mahmoud Mohamed Bahgat
author_sort Heba Abdallah
collection DOAJ
description Abstract An integrated membrane filtration system was developed to make water purity suitable for microbiology/molecular biology research. Water samples were collected from outlets in different buildings of the National Research Center and analyzed for their composition before filtration. An integrated membrane system was developed based on mathematical modeling. Flat sheet membranes were produced, including microfiltration, ultrafiltration, and nanofiltration membranes. The flat sheet membranes were converted to a spiral wound module filter to simulate the local market filters and applied in the integrated membrane system that was designed and installed. The produced water was analyzed and compared to molecular-grade water used in different molecular biology/microbiology applications. Both PCR, agarose gel electrophoresis, bacterial liquid cultures, and viral propagation indicated that treated water using the herein-developed system exhibited comparable performance to the molecular grade water provided with imported reagent kits. So, this research can offer a promising solution for producing high-quality water suitable for sensitive laboratory applications.
format Article
id doaj-art-2841422a69e0444daa96d2fe9c32b791
institution Kabale University
issn 2190-5487
2190-5495
language English
publishDate 2024-10-01
publisher SpringerOpen
record_format Article
series Applied Water Science
spelling doaj-art-2841422a69e0444daa96d2fe9c32b7912024-11-17T12:40:38ZengSpringerOpenApplied Water Science2190-54872190-54952024-10-01141111310.1007/s13201-024-02294-0Integrated membranes system for water application in microbiology/molecular biologyHeba Abdallah0Dina Nadeem Abd-Elshafy1Marwa Shalaby2Kareem Awad3Rola Nadeem4Ahmed Shaban5Mahmoud Mohamed Bahgat6Chemical Engineering and Pilot Plant Department, Engineering and Renewable Energy Research Institute, National Research CentreEnvironmental Virology Laboratory, Department of Water Pollution Research, Environmental and Climate Change Research Institute, National Research CentreChemical Engineering and Pilot Plant Department, Engineering and Renewable Energy Research Institute, National Research CentreResearch Group Immune- and Bio-Markers for Infection, the Centre of Excellent for Advanced Science, National Research CentreResearch Group Immune- and Bio-Markers for Infection, the Centre of Excellent for Advanced Science, National Research CentreEnvironmental Virology Laboratory, Department of Water Pollution Research, Environmental and Climate Change Research Institute, National Research CentreResearch Group Immune- and Bio-Markers for Infection, the Centre of Excellent for Advanced Science, National Research CentreAbstract An integrated membrane filtration system was developed to make water purity suitable for microbiology/molecular biology research. Water samples were collected from outlets in different buildings of the National Research Center and analyzed for their composition before filtration. An integrated membrane system was developed based on mathematical modeling. Flat sheet membranes were produced, including microfiltration, ultrafiltration, and nanofiltration membranes. The flat sheet membranes were converted to a spiral wound module filter to simulate the local market filters and applied in the integrated membrane system that was designed and installed. The produced water was analyzed and compared to molecular-grade water used in different molecular biology/microbiology applications. Both PCR, agarose gel electrophoresis, bacterial liquid cultures, and viral propagation indicated that treated water using the herein-developed system exhibited comparable performance to the molecular grade water provided with imported reagent kits. So, this research can offer a promising solution for producing high-quality water suitable for sensitive laboratory applications.https://doi.org/10.1007/s13201-024-02294-0Integrated filtration systemWater analysisMembrane preparationMolecular biology/microbiology applications
spellingShingle Heba Abdallah
Dina Nadeem Abd-Elshafy
Marwa Shalaby
Kareem Awad
Rola Nadeem
Ahmed Shaban
Mahmoud Mohamed Bahgat
Integrated membranes system for water application in microbiology/molecular biology
Applied Water Science
Integrated filtration system
Water analysis
Membrane preparation
Molecular biology/microbiology applications
title Integrated membranes system for water application in microbiology/molecular biology
title_full Integrated membranes system for water application in microbiology/molecular biology
title_fullStr Integrated membranes system for water application in microbiology/molecular biology
title_full_unstemmed Integrated membranes system for water application in microbiology/molecular biology
title_short Integrated membranes system for water application in microbiology/molecular biology
title_sort integrated membranes system for water application in microbiology molecular biology
topic Integrated filtration system
Water analysis
Membrane preparation
Molecular biology/microbiology applications
url https://doi.org/10.1007/s13201-024-02294-0
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AT kareemawad integratedmembranessystemforwaterapplicationinmicrobiologymolecularbiology
AT rolanadeem integratedmembranessystemforwaterapplicationinmicrobiologymolecularbiology
AT ahmedshaban integratedmembranessystemforwaterapplicationinmicrobiologymolecularbiology
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