Clear Cell Sarcoma of the Soft Tissue in the Distal Phalanx of the Great Toe: A Case Report

Clear cell sarcoma (CCS) is a rare malignant soft tissue tumor originating from neural crest cells. Histologically resembling malignant melanoma but lacking cutaneous precursor lesions, CCS is characterized by a specific chromosomal translocation (t[12;22][q13;q12]). Primarily affecting young adu...

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Bibliographic Details
Main Authors: Heejun Park, Woo Young Kang, Ok Hee Woo, Aeree Kim
Format: Article
Language:English
Published: The Korean Society of Radiology 2024-11-01
Series:Journal of the Korean Society of Radiology
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Online Access:https://doi.org/10.3348/jksr.2024.0083
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Summary:Clear cell sarcoma (CCS) is a rare malignant soft tissue tumor originating from neural crest cells. Histologically resembling malignant melanoma but lacking cutaneous precursor lesions, CCS is characterized by a specific chromosomal translocation (t[12;22][q13;q12]). Primarily affecting young adults, this tumor typically arises in the extremities, especially the knee, foot, and ankle. To our knowledge, distal toe involvement is uncommon. Herein, we present a case initially diagnosed on magnetic resonance imaging as a superficial soft tissue tumor resembling malignant melanoma but subsequently confirmed as CCS of the great toe.
ISSN:2951-0805