EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATURE
The purpose of the present review is to give an update regarding the classification, the epidemiology, the clinical manifestation, the diagnoses, and the treatment of the Rickettsiae species present in the Mediterranean area. We performed a comprehensive search, through electronic databases (Pubm...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2020-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | https://www.mjhid.org/index.php/mjhid/article/view/4260 |
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| author | Andrea De Vito Nicholas Geremia Maria Sabrina Mameli Pier Andrea Serra Vito Fiore Gaia Giovanna Maria Rocchitta Susanna Maria Francesca Nuvoli Renato Lobrano Angela Spanu Antonio Cossu Sergio Babudieri Giordano Maddeddu |
| author_facet | Andrea De Vito Nicholas Geremia Maria Sabrina Mameli Pier Andrea Serra Vito Fiore Gaia Giovanna Maria Rocchitta Susanna Maria Francesca Nuvoli Renato Lobrano Angela Spanu Antonio Cossu Sergio Babudieri Giordano Maddeddu |
| author_sort | Andrea De Vito |
| collection | DOAJ |
| description | The purpose of the present review is to give an update regarding the classification, the epidemiology, the clinical manifestation, the diagnoses, and the treatment of the Rickettsiae species present in the Mediterranean area.
We performed a comprehensive search, through electronic databases (Pubmed – MEDLINE) and search engines (Google Scholar), of peer-reviewed publications (articles, reviews, and books).
The availability of new diagnostic tools, including Polymerase Chain Reaction and nucleotide sequencing has significantly modified the classification of intracellular bacteria, including the order Rickettsiales with more and more new Rickettsia species recognized as human pathogens. Furthermore, emerging Rickettsia species have been found in several countries and are often associated with unique clinical pictures that may challenge the physician in the early detection of the diseases.
Rickettsial infections include a wide spectrum of clinical presentations ranging from a benign to a potentially life treating disease that requires prompt recognition and proper management. Recently, due to the spread of SARS-CoV-2 infection, the differential diagnosis with COVID-19 is of crucial importance. The correct understanding of the clinical features, diagnostic tools, and proper treatment can assist clinicians in the management of Rickettsioses in the Mediterranean area. |
| format | Article |
| id | doaj-art-2820c3f1799349df981e94823f73806d |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2020-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-2820c3f1799349df981e94823f73806d2025-01-02T00:16:55ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062020-08-0112110.4084/mjhid.2020.056EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATUREAndrea De Vito0Nicholas Geremia1Maria Sabrina Mameli2Pier Andrea Serra3Vito Fiore4Gaia Giovanna Maria Rocchitta5Susanna Maria Francesca Nuvoli6Renato Lobrano7Angela Spanu8Antonio Cossu9Sergio Babudieri10Giordano MaddedduUnit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.Unit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.Unit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.Department of Medical, Surgical, and Experimental Sciences, Section of Pharmacology, University of Sassari, V. le S. Pietro 43/B, 07100, Sassari, Italy.Unit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.Department of Medical, Surgical, and Experimental Sciences, Section of Pharmacology, University of Sassari, V. le S. Pietro 43/B, 07100, Sassari, Italy.Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, ItalyDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, ItalyDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, ItalyDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, ItalyUnit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.The purpose of the present review is to give an update regarding the classification, the epidemiology, the clinical manifestation, the diagnoses, and the treatment of the Rickettsiae species present in the Mediterranean area. We performed a comprehensive search, through electronic databases (Pubmed – MEDLINE) and search engines (Google Scholar), of peer-reviewed publications (articles, reviews, and books). The availability of new diagnostic tools, including Polymerase Chain Reaction and nucleotide sequencing has significantly modified the classification of intracellular bacteria, including the order Rickettsiales with more and more new Rickettsia species recognized as human pathogens. Furthermore, emerging Rickettsia species have been found in several countries and are often associated with unique clinical pictures that may challenge the physician in the early detection of the diseases. Rickettsial infections include a wide spectrum of clinical presentations ranging from a benign to a potentially life treating disease that requires prompt recognition and proper management. Recently, due to the spread of SARS-CoV-2 infection, the differential diagnosis with COVID-19 is of crucial importance. The correct understanding of the clinical features, diagnostic tools, and proper treatment can assist clinicians in the management of Rickettsioses in the Mediterranean area.https://www.mjhid.org/index.php/mjhid/article/view/4260RickettsiosisReviewEpidemiologyZoonosisCOVID-19Microbiology |
| spellingShingle | Andrea De Vito Nicholas Geremia Maria Sabrina Mameli Pier Andrea Serra Vito Fiore Gaia Giovanna Maria Rocchitta Susanna Maria Francesca Nuvoli Renato Lobrano Angela Spanu Antonio Cossu Sergio Babudieri Giordano Maddeddu EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATURE Mediterranean Journal of Hematology and Infectious Diseases Rickettsiosis Review Epidemiology Zoonosis COVID-19 Microbiology |
| title | EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATURE |
| title_full | EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATURE |
| title_fullStr | EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATURE |
| title_full_unstemmed | EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATURE |
| title_short | EPIDEMIOLOGY, CLINICAL ASPECTES,LABORATORY DIAGNOSIS AND TREATMENT OF RICKESIAL DISEASES IN THE MEDITERRANEAN AREA DURIN COVID-19 PANDEMIC:A REVIEW OF THE LITERATURE |
| title_sort | epidemiology clinical aspectes laboratory diagnosis and treatment of rickesial diseases in the mediterranean area durin covid 19 pandemic a review of the literature |
| topic | Rickettsiosis Review Epidemiology Zoonosis COVID-19 Microbiology |
| url | https://www.mjhid.org/index.php/mjhid/article/view/4260 |
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