De novo establishment of an ex vivo culture for living myocardial slices applying a microphysiological system – MPSlms

Cardiovascular disease is a global health burden. To develop novel treatment options complex in vitro model systems are needed that resemble the pathophysiological situation ex vivo. Nevertheless, current pre-clinical in vitro models for pharmacological research are limited in complexity. Basic cell...

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Main Authors: Jordan Maria, Schmieder Florian, Waleczek Florian J. G., Polk Christoph, Stucki-Koch Angelika, Philipp Jürgen, Dietzel Leila, Clement Alexander, Behrens Stephan, Thum Thomas, Sonntag Frank, Fiedler Jan
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Current Directions in Biomedical Engineering
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Online Access:https://doi.org/10.1515/cdbme-2024-2085
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