A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction

A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction

Abstract To investigate physiological function of α-synuclein is important for understanding its pathophysiological mechanism in synucleinopathies including Parkinson’s disease. Employing knockout mice, we found that Snac/α-synuclein deletion induced aberrant projection of olfactory sensory neurons...

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Bibliographic Details
Main Authors: Jing Ren, Chao Wu, Mengxia Zeng, Mingqin Qu, Ge Gao, Ning Chen, Jingjing Yue, Yuwen Jiang, Tongfei Zhao, Na Xiang, Fangang Meng, Ling-ling Lu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell & Bioscience
Subjects:
Parkinson’s disease
α-synuclein
Ephs
NCK2
Synucleinopathies
Online Access:https://doi.org/10.1186/s13578-024-01313-6
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https://doi.org/10.1186/s13578-024-01313-6

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