Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease
Abstract Background and Objective Mitochondria are crucial to the function of renal tubular cells, and their dynamic perturbation in many aspects is an important mechanism of diabetic kidney disease (DKD). Single-nucleus RNA sequencing (snRNA-seq) technology is a high-throughput sequencing analysis...
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Main Authors: | Zhen Zhu, Guangxin Luan, Song Wu, Yiyi Song, Shuang Shen, Kaiyue Wu, Shengnan Qian, Weiping Jia, Jun Yin, Tao Ren, Jianping Ye, Li Wei |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-025-06074-5 |
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