Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control Study

Background: Hypertension is a leading risk factor for cardiovascular diseases, and its impact on cardiorespiratory fitness is significant. This study aims to compare the cardiorespiratory responses to treadmill exercise between healthy adults and hypertensive individuals to evaluate the fitness diff...

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Main Authors: Ruchi Kothari, Suryadev A. Vrindavanam, Alekhya Emandi, Rashmita Vakamullu, Mohana Kanthamneni, Sai S. Vemparala
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_1042_24
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author Ruchi Kothari
Suryadev A. Vrindavanam
Alekhya Emandi
Rashmita Vakamullu
Mohana Kanthamneni
Sai S. Vemparala
author_facet Ruchi Kothari
Suryadev A. Vrindavanam
Alekhya Emandi
Rashmita Vakamullu
Mohana Kanthamneni
Sai S. Vemparala
author_sort Ruchi Kothari
collection DOAJ
description Background: Hypertension is a leading risk factor for cardiovascular diseases, and its impact on cardiorespiratory fitness is significant. This study aims to compare the cardiorespiratory responses to treadmill exercise between healthy adults and hypertensive individuals to evaluate the fitness differences between these two groups. Methodology: This case-control study included 100 participants, 50 hypertensive patients, and 50 age- and sex-matched healthy controls. All participants underwent a standardized treadmill exercise test, during which heart rate, blood pressure, and oxygen consumption (VO2 max) were measured. The primary outcomes were the differences in heart rate response, systolic blood pressure, and VO2 max between the two groups. Results: The hypertensive group exhibited significantly higher resting heart rates and systolic blood pressure than the healthy controls (P < 0.01). During exercise, hypertensives showed a blunted heart rate response and lower VO2 max, indicating reduced cardiorespiratory fitness. Recovery time post-exercise was also prolonged in the hypertensive group (P < 0.05). Conclusion: The study highlights significant differences in cardiorespiratory fitness between healthy adults and hypertensive individuals. Hypertensives demonstrate reduced exercise capacity, emphasizing the need for targeted interventions to improve cardiovascular health in this population.
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language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-27e3ba7f4d8043b98cda8dfea902560e2025-01-13T10:06:29ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3559S356110.4103/jpbs.jpbs_1042_24Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control StudyRuchi KothariSuryadev A. VrindavanamAlekhya EmandiRashmita VakamulluMohana KanthamneniSai S. VemparalaBackground: Hypertension is a leading risk factor for cardiovascular diseases, and its impact on cardiorespiratory fitness is significant. This study aims to compare the cardiorespiratory responses to treadmill exercise between healthy adults and hypertensive individuals to evaluate the fitness differences between these two groups. Methodology: This case-control study included 100 participants, 50 hypertensive patients, and 50 age- and sex-matched healthy controls. All participants underwent a standardized treadmill exercise test, during which heart rate, blood pressure, and oxygen consumption (VO2 max) were measured. The primary outcomes were the differences in heart rate response, systolic blood pressure, and VO2 max between the two groups. Results: The hypertensive group exhibited significantly higher resting heart rates and systolic blood pressure than the healthy controls (P < 0.01). During exercise, hypertensives showed a blunted heart rate response and lower VO2 max, indicating reduced cardiorespiratory fitness. Recovery time post-exercise was also prolonged in the hypertensive group (P < 0.05). Conclusion: The study highlights significant differences in cardiorespiratory fitness between healthy adults and hypertensive individuals. Hypertensives demonstrate reduced exercise capacity, emphasizing the need for targeted interventions to improve cardiovascular health in this population.https://journals.lww.com/10.4103/jpbs.jpbs_1042_24blood pressurecardiorespiratory fitnessheart ratehypertensiontreadmill exercisevo2 max
spellingShingle Ruchi Kothari
Suryadev A. Vrindavanam
Alekhya Emandi
Rashmita Vakamullu
Mohana Kanthamneni
Sai S. Vemparala
Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control Study
Journal of Pharmacy and Bioallied Sciences
blood pressure
cardiorespiratory fitness
heart rate
hypertension
treadmill exercise
vo2 max
title Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control Study
title_full Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control Study
title_fullStr Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control Study
title_full_unstemmed Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control Study
title_short Unmasking Fitness in Healthy Adults Versus Hypertensives Through Cardiorespiratory Responses to Treadmill Exercise: A Case-Control Study
title_sort unmasking fitness in healthy adults versus hypertensives through cardiorespiratory responses to treadmill exercise a case control study
topic blood pressure
cardiorespiratory fitness
heart rate
hypertension
treadmill exercise
vo2 max
url https://journals.lww.com/10.4103/jpbs.jpbs_1042_24
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