Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease

Podocytes are extremely important for maintaining the stability of the glomerular filtration barrier,which can lead to glomerular filtration dysfunction and associated kidney disease.Epithelial-mesenchymal transition(EMT)is a manifestation of podocyte injury and one of the initiating factors of vari...

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Main Authors: CHEN Hai-yun, AO Ying, ZHU Ya-nan, WANG Hui
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2020-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/thesisDetails?columnId=57907317&Fpath=home&index=0
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author CHEN Hai-yun
AO Ying
ZHU Ya-nan
WANG Hui
author_facet CHEN Hai-yun
AO Ying
ZHU Ya-nan
WANG Hui
author_sort CHEN Hai-yun
collection DOAJ
description Podocytes are extremely important for maintaining the stability of the glomerular filtration barrier,which can lead to glomerular filtration dysfunction and associated kidney disease.Epithelial-mesenchymal transition(EMT)is a manifestation of podocyte injury and one of the initiating factors of various glomerular diseases.This article focuses on the definition,specific manifestations,inducing factors,mechanisms of occurrence and related glomerular diseases of the podocyte EMT and its prevention and treatment,in order to clarify the recent research progress of podocyte EMT,and provide reference for the treatment of related kidney diseases.
format Article
id doaj-art-27e28d29f20a417e8d6ee96d3b15aca4
institution Kabale University
issn 1671-2390
language zho
publishDate 2020-01-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-27e28d29f20a417e8d6ee96d3b15aca42025-08-20T03:49:02ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902020-01-012042543057907317Podocyte epithelial-mesenchymal transdifferentiation and glomerular diseaseCHEN Hai-yunAO YingZHU Ya-nanWANG HuiPodocytes are extremely important for maintaining the stability of the glomerular filtration barrier,which can lead to glomerular filtration dysfunction and associated kidney disease.Epithelial-mesenchymal transition(EMT)is a manifestation of podocyte injury and one of the initiating factors of various glomerular diseases.This article focuses on the definition,specific manifestations,inducing factors,mechanisms of occurrence and related glomerular diseases of the podocyte EMT and its prevention and treatment,in order to clarify the recent research progress of podocyte EMT,and provide reference for the treatment of related kidney diseases.http://www.lcszb.com/thesisDetails?columnId=57907317&Fpath=home&index=0Podocyte dysplasiaPodocyte EMTGlomerular disease
spellingShingle CHEN Hai-yun
AO Ying
ZHU Ya-nan
WANG Hui
Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease
Linchuang shenzangbing zazhi
Podocyte dysplasia
Podocyte EMT
Glomerular disease
title Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease
title_full Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease
title_fullStr Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease
title_full_unstemmed Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease
title_short Podocyte epithelial-mesenchymal transdifferentiation and glomerular disease
title_sort podocyte epithelial mesenchymal transdifferentiation and glomerular disease
topic Podocyte dysplasia
Podocyte EMT
Glomerular disease
url http://www.lcszb.com/thesisDetails?columnId=57907317&Fpath=home&index=0
work_keys_str_mv AT chenhaiyun podocyteepithelialmesenchymaltransdifferentiationandglomerulardisease
AT aoying podocyteepithelialmesenchymaltransdifferentiationandglomerulardisease
AT zhuyanan podocyteepithelialmesenchymaltransdifferentiationandglomerulardisease
AT wanghui podocyteepithelialmesenchymaltransdifferentiationandglomerulardisease