IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?

Despite significant achievements in the management of patients with cardiac vascular pathology, this type of disorders remains to be the major cause of death all over the world. Patients undergoing surgery and suffering from cardiac vascular diseases face a high risk to develop post-operative compli...

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Main Authors: V. V. Lomivorotov, S. M. Efremov, M. N. Аbubаkirov, D. N. Merekin
Format: Article
Language:Russian
Published: New Terra Publishing House 2018-07-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/249
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author V. V. Lomivorotov
S. M. Efremov
M. N. Аbubаkirov
D. N. Merekin
author_facet V. V. Lomivorotov
S. M. Efremov
M. N. Аbubаkirov
D. N. Merekin
author_sort V. V. Lomivorotov
collection DOAJ
description Despite significant achievements in the management of patients with cardiac vascular pathology, this type of disorders remains to be the major cause of death all over the world. Patients undergoing surgery and suffering from cardiac vascular diseases face a high risk to develop post-operative complications and lethal outcome and about half of the post-operative lethal cases after non-cardiac surgery are caused by cardiac vascular complications. Inhibitors of angiotensin-converting enzyme as well as angiotensin II receptor blockers are the ones of the most frequently used drugs in cardiology; they have been proved to slow down the progress of the disease, improve life quality and reduce mortality. However, the use of these drugs in pre-operative period can be associated with such adverse events as hypotension and post-operative renal dysfunction. Thus, it is necessary to justify therapy with blockers of renin-angiotensin-aldosterone system in the peri-operative period in the patients undergoing cardiac and non-cardiac surgery.
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institution Kabale University
issn 2078-5658
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language Russian
publishDate 2018-07-01
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record_format Article
series Вестник анестезиологии и реаниматологии
spelling doaj-art-27a80f5f2af043bebfac6bd0dc9af8c32025-08-20T03:42:45ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532018-07-01153566110.21292/2078-5658-2018-15-3-56-61240IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?V. V. Lomivorotov0S. M. Efremov1M. N. Аbubаkirov2D. N. Merekin3E.N. Meshalkin Research Institute of Blood Circulation PathologyE.N. Meshalkin Research Institute of Blood Circulation PathologyE.N. Meshalkin Research Institute of Blood Circulation PathologyE.N. Meshalkin Research Institute of Blood Circulation PathologyDespite significant achievements in the management of patients with cardiac vascular pathology, this type of disorders remains to be the major cause of death all over the world. Patients undergoing surgery and suffering from cardiac vascular diseases face a high risk to develop post-operative complications and lethal outcome and about half of the post-operative lethal cases after non-cardiac surgery are caused by cardiac vascular complications. Inhibitors of angiotensin-converting enzyme as well as angiotensin II receptor blockers are the ones of the most frequently used drugs in cardiology; they have been proved to slow down the progress of the disease, improve life quality and reduce mortality. However, the use of these drugs in pre-operative period can be associated with such adverse events as hypotension and post-operative renal dysfunction. Thus, it is necessary to justify therapy with blockers of renin-angiotensin-aldosterone system in the peri-operative period in the patients undergoing cardiac and non-cardiac surgery.https://www.vair-journal.com/jour/article/view/249inhibitors of angiotensin-converting enzymeangiotensin ii receptor blockerscardiac vascular surgerygeneral surgery
spellingShingle V. V. Lomivorotov
S. M. Efremov
M. N. Аbubаkirov
D. N. Merekin
IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?
Вестник анестезиологии и реаниматологии
inhibitors of angiotensin-converting enzyme
angiotensin ii receptor blockers
cardiac vascular surgery
general surgery
title IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?
title_full IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?
title_fullStr IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?
title_full_unstemmed IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?
title_short IS IT WORTH TO DISCONTINUE DRUGS BLOCKING THE ACTIVITY OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PERI-OPERATIVE PERIOD?
title_sort is it worth to discontinue drugs blocking the activity of renin angiotensin aldosterone system in the peri operative period
topic inhibitors of angiotensin-converting enzyme
angiotensin ii receptor blockers
cardiac vascular surgery
general surgery
url https://www.vair-journal.com/jour/article/view/249
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AT mnabubakirov isitworthtodiscontinuedrugsblockingtheactivityofreninangiotensinaldosteronesystemintheperioperativeperiod
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