Spatial Transcriptomics in Inflammatory Skin Diseases Using GeoMx Digital Spatial Profiling: A Practical Guide for Applications in Dermatology

Spatial Transcriptomics in Inflammatory Skin Diseases Using GeoMx Digital Spatial Profiling: A Practical Guide for Applications in Dermatology

The spatial organization of the skin is critical for its function. In particular, the skin immune microenvironment is arranged spatially and temporally, such that imbalances in the immune milieu are indicative of disease. Spatial transcriptomic platforms are helping to provide additional insights in...

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Bibliographic Details
Main Authors: Christina Cho, Nazgol-Sadat Haddadi, Michal Kidacki, Gavitt A. Woodard, Saeed Shakiba, Ümmügülsüm Yıldız-Altay, Jillian M. Richmond, Matthew D. Vesely
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:JID Innovations
Subjects:
Cutaneous lupus
Digital spatial profiling
Lichen planus
Psoriasis
Spatial transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2667026724000651
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