GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stress

Low temperature is a critical abiotic stress during the early growth stages of cotton, affecting crop establishment and causing yield reduction. A thorough insight into the genetic factors governing cold tolerance is critical for formulating breeding strategies aiming for enhanced cold-tolerance. Th...

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Main Authors: Jianbin Li, Xiaokang Feng, Bangxin Chen, Qian-Hao Zhu, Xinyu Zhang, Yonglin Yang, Fei Xue, Jie Sun
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Plant Stress
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667064X25002003
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author Jianbin Li
Xiaokang Feng
Bangxin Chen
Qian-Hao Zhu
Xinyu Zhang
Yonglin Yang
Fei Xue
Jie Sun
author_facet Jianbin Li
Xiaokang Feng
Bangxin Chen
Qian-Hao Zhu
Xinyu Zhang
Yonglin Yang
Fei Xue
Jie Sun
author_sort Jianbin Li
collection DOAJ
description Low temperature is a critical abiotic stress during the early growth stages of cotton, affecting crop establishment and causing yield reduction. A thorough insight into the genetic factors governing cold tolerance is critical for formulating breeding strategies aiming for enhanced cold-tolerance. This study measured the primary root length (RL), fresh weight (FW), and dry weight (DW) of 343 upland cotton (Gossypium hirsutum L.) germplasm under sustained low-temperature stress during the seedling stage. The single nucleotide polymorphisms (SNPs) identified based on resequencing of the 343 accessions were used in a genome-wide association analysis of the three traits, which identified two, six and eight SNPs significantly associated with RL, FW, and DW, respectively. Two major loci on chromosomes A03 and D04 contributing to FW- and DW-based cold tolerance were evident due to their occurrence in at least two datasets. Within these two loci, multiple genes were found to be cold responsive, with GH_A03G1754 being a potentially positive contributor of cold tolerance, because silencing the gene in cold-tolerant variety reduced its cold tolerance. This study provides molecular markers and candidate gene for molecular breeding of cold tolerance in cotton.
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institution Kabale University
issn 2667-064X
language English
publishDate 2025-09-01
publisher Elsevier
record_format Article
series Plant Stress
spelling doaj-art-276290cd7e4842f8b07c5516d079514b2025-08-23T04:49:31ZengElsevierPlant Stress2667-064X2025-09-011710093210.1016/j.stress.2025.100932GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stressJianbin Li0Xiaokang Feng1Bangxin Chen2Qian-Hao Zhu3Xinyu Zhang4Yonglin Yang5Fei Xue6Jie Sun7The Key Oasis Eco-Agriculture Laboratory of Xinjiang Production and Construction Group, College of Agriculture, Shihezi University, Shihezi, Xinjiang 832000, ChinaThe Key Oasis Eco-Agriculture Laboratory of Xinjiang Production and Construction Group, College of Agriculture, Shihezi University, Shihezi, Xinjiang 832000, ChinaThe Key Oasis Eco-Agriculture Laboratory of Xinjiang Production and Construction Group, College of Agriculture, Shihezi University, Shihezi, Xinjiang 832000, ChinaCSIRO Agriculture and Food, GPO Box 1700, Canberra 2601, AustraliaThe Key Oasis Eco-Agriculture Laboratory of Xinjiang Production and Construction Group, College of Agriculture, Shihezi University, Shihezi, Xinjiang 832000, ChinaShihezi Academy of Agricultural Sciences, Shihezi, Xinjiang 832000, ChinaThe Key Oasis Eco-Agriculture Laboratory of Xinjiang Production and Construction Group, College of Agriculture, Shihezi University, Shihezi, Xinjiang 832000, China; Corresponding authors.The Key Oasis Eco-Agriculture Laboratory of Xinjiang Production and Construction Group, College of Agriculture, Shihezi University, Shihezi, Xinjiang 832000, China; Corresponding authors.Low temperature is a critical abiotic stress during the early growth stages of cotton, affecting crop establishment and causing yield reduction. A thorough insight into the genetic factors governing cold tolerance is critical for formulating breeding strategies aiming for enhanced cold-tolerance. This study measured the primary root length (RL), fresh weight (FW), and dry weight (DW) of 343 upland cotton (Gossypium hirsutum L.) germplasm under sustained low-temperature stress during the seedling stage. The single nucleotide polymorphisms (SNPs) identified based on resequencing of the 343 accessions were used in a genome-wide association analysis of the three traits, which identified two, six and eight SNPs significantly associated with RL, FW, and DW, respectively. Two major loci on chromosomes A03 and D04 contributing to FW- and DW-based cold tolerance were evident due to their occurrence in at least two datasets. Within these two loci, multiple genes were found to be cold responsive, with GH_A03G1754 being a potentially positive contributor of cold tolerance, because silencing the gene in cold-tolerant variety reduced its cold tolerance. This study provides molecular markers and candidate gene for molecular breeding of cold tolerance in cotton.http://www.sciencedirect.com/science/article/pii/S2667064X25002003Upland cottonSeedling stageLow temperature stressGenome-wide association
spellingShingle Jianbin Li
Xiaokang Feng
Bangxin Chen
Qian-Hao Zhu
Xinyu Zhang
Yonglin Yang
Fei Xue
Jie Sun
GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stress
Plant Stress
Upland cotton
Seedling stage
Low temperature stress
Genome-wide association
title GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stress
title_full GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stress
title_fullStr GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stress
title_full_unstemmed GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stress
title_short GWAS analysis reveals a novel ERF family gene GH_A03G1754 in upland cotton under cold stress
title_sort gwas analysis reveals a novel erf family gene gh a03g1754 in upland cotton under cold stress
topic Upland cotton
Seedling stage
Low temperature stress
Genome-wide association
url http://www.sciencedirect.com/science/article/pii/S2667064X25002003
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