Hypoxia Activates FGF-23-ERK/MAPK Signaling Pathway in Ischemia-Reperfusion-Induced Acute Kidney Injury

Hypoxia Activates FGF-23-ERK/MAPK Signaling Pathway in Ischemia-Reperfusion-Induced Acute Kidney Injury

Introduction: Both hypoxia and fibroblast growth factor-23 (FGF-23) are key factors in ischemia-reperfusion (I/R)-induced acute kidney injury (AKI). This study aimed to explore the relationship between hypoxia and FGF-23 in AKI. Methods: An I/R-AKI animal model was established using male BALB/c mice...

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Bibliographic Details
Main Authors: Weihua Liu, Miao Lin, Yiping Dai, Fuyuan Hong
Format: Article
Language:English
Published: Karger Publishers 2024-10-01
Series:Kidney & Blood Pressure Research
Subjects:
ischemia-reperfusion
hypoxia
kidney injury
erk/mark
fgf-23
Online Access:https://beta.karger.com/Article/FullText/541388
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