Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression

Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression

Cytokines play a crucial role in mediating cell communication within the tumor microenvironment (TME). Tumor-associated macrophages are particularly influential in the regulation of immunosuppressive cytokines, thereby supporting tumor metastasis. The upregulation of Th2 cytokines in cancer cells is...

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Bibliographic Details
Main Authors:	Shankar Suman, Wendy K. Nevala, Alexey A. Leontovich, James W. Jakub, Liyi Geng, Sarah A. McLaughlin, Svetomir N. Markovic
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Molecular Biosciences
Subjects:	tumor-promoting macrophage cytokines extracellular vesicles melanoma immunosuppression tumor microenvironment
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2024.1522717/full
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