German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0

This guideline for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus was developed and managed by the German Guideline Program in Oncology (GGPO) of the Association of the Scientific Medical Societies in Germany (AWMF), German Cancer Society (DKG), and German...

Full description

Saved in:
Bibliographic Details
Main Authors: M.P. Ebert, W. Fischbach, S. Hollerbach, J. Höppner, D. Lorenz, M. Stahl, M. Stuschke, O. Pech, U. Vanhoefer, C. Bruns, C. Ell, M. Follmann, U. Goerling, L. Grenacher, J. Haardt, A.H. Hölscher, R. Hummel, W.T. Knoefel, J. Körber, R. Langer, P. Lenz, F. Lordick, S. Lorenzen, A.G. Meining, J. Menzel, H.-J. Meyer, N.H. Nicolay, M. Nothacker, U. Nöthlings, H. Schmidberger, M. Schmidt, T. Seufferlein, P. Thuss-Patience, J. Trojan, A. Weimann, L. Klug, P. Lynen, T. Zhan, Q. Xiao, R. Porschen
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:ESMO Gastrointestinal Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949819824000736
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850060604372418560
author M.P. Ebert
W. Fischbach
S. Hollerbach
J. Höppner
D. Lorenz
M. Stahl
M. Stuschke
O. Pech
U. Vanhoefer
C. Bruns
C. Ell
M. Follmann
U. Goerling
L. Grenacher
J. Haardt
A.H. Hölscher
R. Hummel
W.T. Knoefel
J. Körber
R. Langer
P. Lenz
F. Lordick
S. Lorenzen
A.G. Meining
J. Menzel
H.-J. Meyer
N.H. Nicolay
M. Nothacker
U. Nöthlings
H. Schmidberger
M. Schmidt
T. Seufferlein
P. Thuss-Patience
J. Trojan
A. Weimann
L. Klug
P. Lynen
T. Zhan
Q. Xiao
R. Porschen
author_facet M.P. Ebert
W. Fischbach
S. Hollerbach
J. Höppner
D. Lorenz
M. Stahl
M. Stuschke
O. Pech
U. Vanhoefer
C. Bruns
C. Ell
M. Follmann
U. Goerling
L. Grenacher
J. Haardt
A.H. Hölscher
R. Hummel
W.T. Knoefel
J. Körber
R. Langer
P. Lenz
F. Lordick
S. Lorenzen
A.G. Meining
J. Menzel
H.-J. Meyer
N.H. Nicolay
M. Nothacker
U. Nöthlings
H. Schmidberger
M. Schmidt
T. Seufferlein
P. Thuss-Patience
J. Trojan
A. Weimann
L. Klug
P. Lynen
T. Zhan
Q. Xiao
R. Porschen
author_sort M.P. Ebert
collection DOAJ
description This guideline for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus was developed and managed by the German Guideline Program in Oncology (GGPO) of the Association of the Scientific Medical Societies in Germany (AWMF), German Cancer Society (DKG), and German Cancer Aid (DKH). The guideline commission comprised multidisciplinary experts from various professional associations and organizations involved in the management of esophageal cancer, as well as a patient representative. Quality of the evidence is presented using Oxford evidence-based medicine system, and recommendations were graded in a formal consensus process using a recommendation grading scheme.
format Article
id doaj-art-266494e367aa49fd841c47bcaecd2802
institution DOAJ
issn 2949-8198
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series ESMO Gastrointestinal Oncology
spelling doaj-art-266494e367aa49fd841c47bcaecd28022025-08-20T02:50:30ZengElsevierESMO Gastrointestinal Oncology2949-81982025-03-01710011210.1016/j.esmogo.2024.100112German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0M.P. Ebert0W. Fischbach1S. Hollerbach2J. Höppner3D. Lorenz4M. Stahl5M. Stuschke6O. Pech7U. Vanhoefer8C. Bruns9C. Ell10M. Follmann11U. Goerling12L. Grenacher13J. Haardt14A.H. Hölscher15R. Hummel16W.T. Knoefel17J. Körber18R. Langer19P. Lenz20F. Lordick21S. Lorenzen22A.G. Meining23J. Menzel24H.-J. Meyer25N.H. Nicolay26M. Nothacker27U. Nöthlings28H. Schmidberger29M. Schmidt30T. Seufferlein31P. Thuss-Patience32J. Trojan33A. Weimann34L. Klug35P. Lynen36T. Zhan37Q. Xiao38R. Porschen39II. Medizinische Klinik, Medizinische Fakultät Mannheim, Universitätsmedizin, Universität Heidelberg, Mannheim, Germany; DKFZ-Hector Krebsinstitut an der Universitätsmedizin Mannheim, Mannheim, Germany; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany; Correspondence to: Prof. Dr Matthias P. Ebert, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany Tel: +49-621-383-3284; Fax: +49-621-383-3805.Deutsche Gesellschaft zur Bekämpfung der Krankheiten von Magen, Darm und Leber sowie von Störungen des Stoffwechsels und der Ernährung (Gastro-Liga) e. V., Giessen, GermanyKlinik für Gastroenterologie, Allgemeines Krankenhaus Celle, Celle, GermanyUniversitätsklinik für Allgemein- und Viszeralchirurgie, Universitätsklinikum OWL, Campus Lippe, Detmold, GermanyChirurgische Klinik I, Allgemein-, Viszeral- und Thoraxchirurgie, Klinikum Darmstadt, Darmstadt, GermanyKlinik für Internistische Onkologie und onkologische Palliativmedizin, Evang. Huyssensstiftung, Evang. Kliniken Essen-Mitte, Essen, GermanyKlinik und Poliklinik für Strahlentherapie, Universitätsklinikum Essen, Essen, GermanyKlinik für Gastroenterologie und Interventionelle Endoskopie, Krankenhaus Barmherzige Brüder, Regensburg, GermanyKlinik für Hämatologie und Onkologie, Katholisches Marienkrankenhaus, Hamburg, GermanyKlinik und Poliklinik für Allgemein-, Viszeral-, Tumor- und Transplantationschirurgie, Universitätsklinikum Köln, Köln, GermanyMedizinische Klinik II/IV, Sana Klinikum Offenbach, Offenbach, GermanyDeutsche Krebsgesellschaft e.V., Berlin, GermanyCharité Comprehensive Cancer Center, Charité—Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, GermanyConradia Radiologie, München, GermanyDeutsche Gesellschaft für Ernährung e.V. (DGE), Bonn, GermanyKlinik für Allgemein-, Viszeral- und Unfallchirurgie - Sektionsleiter Contilia Zentrum für Speiseröhrenerkrankungen, Elisabeth-Krankenhaus Essen, Essen, GermanyKlinik und Poliklinik für Allgemeine Chirurgie Viszeral-, Thorax- und Gefäßchirurgie, Universitätsmedizin Greifswald, Greifswald, GermanyKlinik für Allgemein-, Viszeral- und Kinderchirurgie, Universitätsklinikum Düsseldorf, Düsseldorf, GermanyKlinik für Gastroenterologie, Rehabilitationsklinik Nahetal, Bad Kreuznach, GermanyMed. Campus III, Klinik für Allgemein- und Viszeralchirurgie, Kepler Universitätsklinikum, Linz, AustriaZentrale Einrichtung Palliativmedizin, Universitätsklinikum Münster, Münster, GermanyUniversitäres Krebszentrum Leipzig, Universitätsklinikum Leipzig, Leipzig, GermanyIII. Medizinische Klinik, Klinikum rechts der Isar, TU München, München, GermanyMedizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, GermanyMedizinische Klinik II, Klinikum Ingolstadt, Ingolstadt, GermanyDeutsche Gesellschaft für Chirurgie, Berlin, GermanyKlinik und Poliklinik für Strahlentherapie, Universitätsklinikum Leipzig, LeipzigAWMF-Institut für Medizinisches Wissensmanagement, Berlin, GermanyInstitut für Ernährungs- und Lebensmittelwissenschaften, Universitätsklinikum Bonn, Bonn, GermanyKlinik für Radioonkologie und Strahlentherapie, Universitätsmedizin Mainz, Mainz, GermanyKlinik und Poliklinik für Nuklearmedizin, Universität zu Köln, Medizinische Fakultät und Universitätsklinik Köln, Köln, GermanyKlinik für Innere Medizin I, Universitätsklinikum Ulm, Ulm, GermanyKlinik für Innere Medizin – Hämatologie, Onkologie und Palliativmedizin, Klinikum im Friedrichshain, Berlin, GermanyMedizinische Klinik I, Universitätsklinikum Frankfurt, Frankfurt, GermanyKlinik für Allgemein-, Viszeral- und Onkologische Chirurgie, Klinikum St. Georg, Leipzig, GermanyDeutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten e.V. (DGVS), Berlin, GermanyDeutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten e.V. (DGVS), Berlin, GermanyII. Medizinische Klinik, Medizinische Fakultät Mannheim, Universitätsmedizin, Universität Heidelberg, Mannheim, Germany; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, GermanyII. Medizinische Klinik, Medizinische Fakultät Mannheim, Universitätsmedizin, Universität Heidelberg, Mannheim, GermanyGastroenterologische Praxis am Kreiskrankenhaus Osterholz, Osterholz-Scharmbeck, GermanyThis guideline for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus was developed and managed by the German Guideline Program in Oncology (GGPO) of the Association of the Scientific Medical Societies in Germany (AWMF), German Cancer Society (DKG), and German Cancer Aid (DKH). The guideline commission comprised multidisciplinary experts from various professional associations and organizations involved in the management of esophageal cancer, as well as a patient representative. Quality of the evidence is presented using Oxford evidence-based medicine system, and recommendations were graded in a formal consensus process using a recommendation grading scheme.http://www.sciencedirect.com/science/article/pii/S2949819824000736esophageal carcinomaBarrett’s esophagusperioperative chemotherapyneoadjuvant chemoradiationmultimodal therapyimmune therapy
spellingShingle M.P. Ebert
W. Fischbach
S. Hollerbach
J. Höppner
D. Lorenz
M. Stahl
M. Stuschke
O. Pech
U. Vanhoefer
C. Bruns
C. Ell
M. Follmann
U. Goerling
L. Grenacher
J. Haardt
A.H. Hölscher
R. Hummel
W.T. Knoefel
J. Körber
R. Langer
P. Lenz
F. Lordick
S. Lorenzen
A.G. Meining
J. Menzel
H.-J. Meyer
N.H. Nicolay
M. Nothacker
U. Nöthlings
H. Schmidberger
M. Schmidt
T. Seufferlein
P. Thuss-Patience
J. Trojan
A. Weimann
L. Klug
P. Lynen
T. Zhan
Q. Xiao
R. Porschen
German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0
ESMO Gastrointestinal Oncology
esophageal carcinoma
Barrett’s esophagus
perioperative chemotherapy
neoadjuvant chemoradiation
multimodal therapy
immune therapy
title German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0
title_full German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0
title_fullStr German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0
title_full_unstemmed German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0
title_short German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus—version 4.0
title_sort german guidelines for the diagnosis and treatment of squamous cell carcinoma and adenocarcinoma of the esophagus version 4 0
topic esophageal carcinoma
Barrett’s esophagus
perioperative chemotherapy
neoadjuvant chemoradiation
multimodal therapy
immune therapy
url http://www.sciencedirect.com/science/article/pii/S2949819824000736
work_keys_str_mv AT mpebert germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT wfischbach germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT shollerbach germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT jhoppner germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT dlorenz germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT mstahl germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT mstuschke germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT opech germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT uvanhoefer germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT cbruns germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT cell germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT mfollmann germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT ugoerling germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT lgrenacher germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT jhaardt germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT ahholscher germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT rhummel germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT wtknoefel germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT jkorber germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT rlanger germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT plenz germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT flordick germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT slorenzen germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT agmeining germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT jmenzel germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT hjmeyer germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT nhnicolay germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT mnothacker germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT unothlings germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT hschmidberger germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT mschmidt germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT tseufferlein germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT pthusspatience germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT jtrojan germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT aweimann germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT lklug germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT plynen germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT tzhan germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT qxiao germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40
AT rporschen germanguidelinesforthediagnosisandtreatmentofsquamouscellcarcinomaandadenocarcinomaoftheesophagusversion40