UBC9 overexpression promotes proliferation and metastasis in gastric cancer via ATF2

UBC9 overexpression promotes proliferation and metastasis in gastric cancer via ATF2

Abstract Gastric cancer remains a leading cause of cancer-related mortality worldwide, characterized by poor prognosis due to its aggressive nature and high metastatic potential. While the E2-conjugating enzyme UBE2I (UBC9), essential for SUMOylation, has been implicated in various cancers, its prec...

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Bibliographic Details
Main Authors: QingShui Wang, ShengZhao Li, YiNing Xu, Yuluo Chen, Chao Xu, QiuYan He, Yan Ye, YiMin Huang, Yue Wu, KeJia Guo, YaJuan Wei, Yide Huang, Yan Liu, Qing Lin, Shanshan Wang, Feng Li, Minghan Huang, FangQin Xue, Yao Lin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:World Journal of Surgical Oncology
Subjects:
Gastric cancer
UBC9
SUMOylation
ATF2
Prognosis
Online Access:https://doi.org/10.1186/s12957-025-03922-y
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