Associations of gut microbiota with disease development, disease activity, and therapeutic effects in patients with systemic lupus erythematosus

Associations of gut microbiota with disease development, disease activity, and therapeutic effects in patients with systemic lupus erythematosus

Abstract Altered gut microbiota is linked to systemic lupus erythematosus (SLE), but its association with disease development, disease activity, and post-intervention changes remains unclear. We compared new-onset SLE (NOSLE, n = 25), SLE in remission (RemSLE, n = 30), and healthy controls (HC, n = ...

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Main Authors: Junko Nishio, Hiroshi Sato, Eri Watanabe, Hiroaki Masuoka, Kotaro Aoki, Mai Kawazoe, Risa Wakiya, Soichi Yamada, Sei Muraoka, Shotaro Masuoka, Tomoki Hayashi, Satoshi Mizutani, Zento Yamada, Keiko Koshiba, Izumi Irita, Miwa Kanaji, Karin Furukawa, Nobuyuki Yajima, Hiroaki Dobashi, Wataru Hirose, Yoshikazu Ishii, Wataru Suda, Toshihiro Nanki
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Systemic lupus erythematosus
Gut microbiota
Butyrate-producing bacteria
[Eubacterium] rectale
Hungatella effluvii
Streptococcus
Online Access:https://doi.org/10.1038/s41598-024-83835-0
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