Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a review

The prevalence of degenerative orthopaedic diseases, such as osteoarthritis, osteoporosis, and intervertebral disc disease, has increased due to the increasing prevalence and unsatisfactory therapeutic methods. Recently, different types of bioactive nanomaterials, such as iron oxide nanoparticles (I...

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Main Authors: XL Zhu, QC Fu, LF Jiang, LM Zheng
Format: Article
Language:English
Published: Forum Multimedia Publishing LLC 2024-08-01
Series:European Cells & Materials
Subjects:
Online Access:https://www.ecmjournal.org/papers/vol048/vol048a04.php
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author XL Zhu
QC Fu
LF Jiang
LM Zheng
author_facet XL Zhu
QC Fu
LF Jiang
LM Zheng
author_sort XL Zhu
collection DOAJ
description The prevalence of degenerative orthopaedic diseases, such as osteoarthritis, osteoporosis, and intervertebral disc disease, has increased due to the increasing prevalence and unsatisfactory therapeutic methods. Recently, different types of bioactive nanomaterials, such as iron oxide nanoparticles (IONPs), have raised much concern due to their ability to positively regulate the bone remodelling balance. Due to their magnetic characteristics, IONPs have been applied in magnetic resonance imaging in the clinic, but their ability to treat degenerative orthopaedic diseases has recently been shown both in vitro and in vivo. However, a comprehensive review of the potential utilization of IONPs in the orthopaedic field is lacking. Here, we summarize previous works in this review and discuss future research directions in this field.
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institution Kabale University
issn 1473-2262
language English
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record_format Article
series European Cells & Materials
spelling doaj-art-2603fb8281c648d99bfde1d9568e722c2024-12-17T09:33:20ZengForum Multimedia Publishing LLCEuropean Cells & Materials1473-22622024-08-0148456510.22203/eCM.v048a04Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a reviewXL ZhuQC FuLF JiangLM ZhengThe prevalence of degenerative orthopaedic diseases, such as osteoarthritis, osteoporosis, and intervertebral disc disease, has increased due to the increasing prevalence and unsatisfactory therapeutic methods. Recently, different types of bioactive nanomaterials, such as iron oxide nanoparticles (IONPs), have raised much concern due to their ability to positively regulate the bone remodelling balance. Due to their magnetic characteristics, IONPs have been applied in magnetic resonance imaging in the clinic, but their ability to treat degenerative orthopaedic diseases has recently been shown both in vitro and in vivo. However, a comprehensive review of the potential utilization of IONPs in the orthopaedic field is lacking. Here, we summarize previous works in this review and discuss future research directions in this field.https://www.ecmjournal.org/papers/vol048/vol048a04.phpiron oxide nanoparticlesmagnetismmolecular diagnosisorthopaedic diseases
spellingShingle XL Zhu
QC Fu
LF Jiang
LM Zheng
Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a review
European Cells & Materials
iron oxide nanoparticles
magnetism
molecular diagnosis
orthopaedic diseases
title Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a review
title_full Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a review
title_fullStr Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a review
title_full_unstemmed Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a review
title_short Iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases: a review
title_sort iron oxide nanoparticles for diagnosing and treating degenerative orthopaedic diseases a review
topic iron oxide nanoparticles
magnetism
molecular diagnosis
orthopaedic diseases
url https://www.ecmjournal.org/papers/vol048/vol048a04.php
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AT qcfu ironoxidenanoparticlesfordiagnosingandtreatingdegenerativeorthopaedicdiseasesareview
AT lfjiang ironoxidenanoparticlesfordiagnosingandtreatingdegenerativeorthopaedicdiseasesareview
AT lmzheng ironoxidenanoparticlesfordiagnosingandtreatingdegenerativeorthopaedicdiseasesareview