Influence of exogenous glutathione on the system of antioxidant protection of the body in case of comorbid course of chronic obstructive pulmonary disease and chronic pancreatitis
Aim. To study the condition of oxidant-antioxidant system in patients with comorbid course of chronic obstructive pulmonary disease (COPD) and chronic pancreatitis (CP) with oral administration of glutathione. Methods and results. 60 patients with COPD (GOLD1-2, В stage) were examined in the phas...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Zaporizhzhia State Medical and Pharmaceutical University
2015-08-01
|
| Series: | Zaporožskij Medicinskij Žurnal |
| Subjects: | |
| Online Access: | http://zmj.zsmu.edu.ua/article/view/50273/47712 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Aim. To study the condition of oxidant-antioxidant system in patients with comorbid course of chronic obstructive pulmonary disease (COPD) and chronic pancreatitis (CP) with oral administration of glutathione.
Methods and results. 60 patients with COPD (GOLD1-2, В stage) were examined in the phase of non-infectious exacerbation with comorbid CP in the phase of exacerbation were divided into 2 groups. The main group (2, M) received therapy with hepaval (reduced glutathione per 250 mg twice a day) during 30 days. A tendency to increased activity of reduced glutathione in 1,2 and 1,6 times in the control and main groups was observed (р<0,05).
Conclusion. Treatment with hepaval promotes intensity of LPO processes decrease and restoration of the main factor of the antioxidant protective system in the blood – reduced glutathione. |
|---|---|
| ISSN: | 2306-4145 2310-1210 |