Effect of Different Pediatric Medications on RMGIC: A Comparative Study

Introduction: This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material’s durability and effective...

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Main Authors: Ahtesham A. Qurishi, Mohammed S. Al Dira, Amal H. Sholan, Shahad E. Abzoah, Mahdi A. Hakami, Emad Malhan, Shahad M. Moafa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_688_24
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author Ahtesham A. Qurishi
Mohammed S. Al Dira
Amal H. Sholan
Shahad E. Abzoah
Mahdi A. Hakami
Emad Malhan
Shahad M. Moafa
author_facet Ahtesham A. Qurishi
Mohammed S. Al Dira
Amal H. Sholan
Shahad E. Abzoah
Mahdi A. Hakami
Emad Malhan
Shahad M. Moafa
author_sort Ahtesham A. Qurishi
collection DOAJ
description Introduction: This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material’s durability and effectiveness. Methodology: Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey’s test. Results: All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes. Conclusion: Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.
format Article
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institution Kabale University
issn 0976-4879
0975-7406
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-25932ab8604143e198f08850836369472025-01-12T14:10:07ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3185S318710.4103/jpbs.jpbs_688_24Effect of Different Pediatric Medications on RMGIC: A Comparative StudyAhtesham A. QurishiMohammed S. Al DiraAmal H. SholanShahad E. AbzoahMahdi A. HakamiEmad MalhanShahad M. MoafaIntroduction: This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material’s durability and effectiveness. Methodology: Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey’s test. Results: All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes. Conclusion: Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.https://journals.lww.com/10.4103/jpbs.jpbs_688_24dental restorationsmicrohardnesspediatric medicationsrmgicsurface roughness
spellingShingle Ahtesham A. Qurishi
Mohammed S. Al Dira
Amal H. Sholan
Shahad E. Abzoah
Mahdi A. Hakami
Emad Malhan
Shahad M. Moafa
Effect of Different Pediatric Medications on RMGIC: A Comparative Study
Journal of Pharmacy and Bioallied Sciences
dental restorations
microhardness
pediatric medications
rmgic
surface roughness
title Effect of Different Pediatric Medications on RMGIC: A Comparative Study
title_full Effect of Different Pediatric Medications on RMGIC: A Comparative Study
title_fullStr Effect of Different Pediatric Medications on RMGIC: A Comparative Study
title_full_unstemmed Effect of Different Pediatric Medications on RMGIC: A Comparative Study
title_short Effect of Different Pediatric Medications on RMGIC: A Comparative Study
title_sort effect of different pediatric medications on rmgic a comparative study
topic dental restorations
microhardness
pediatric medications
rmgic
surface roughness
url https://journals.lww.com/10.4103/jpbs.jpbs_688_24
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