Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature
Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycl...
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| Format: | Article |
| Language: | English |
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Korean Society of Traumatology
2019-06-01
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| Series: | Journal of Trauma and Injury |
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| Online Access: | http://www.jtraumainj.org/upload/pdf/jti-32-111.pdf |
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| author | Jayaramakrishna Depa George Coritsidis |
| author_facet | Jayaramakrishna Depa George Coritsidis |
| author_sort | Jayaramakrishna Depa |
| collection | DOAJ |
| description | Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD. |
| format | Article |
| id | doaj-art-2524c4a4acbb40118ae3c3afa0697a27 |
| institution | Kabale University |
| issn | 1738-8767 2287-1683 |
| language | English |
| publishDate | 2019-06-01 |
| publisher | Korean Society of Traumatology |
| record_format | Article |
| series | Journal of Trauma and Injury |
| spelling | doaj-art-2524c4a4acbb40118ae3c3afa0697a272025-01-06T01:15:48ZengKorean Society of TraumatologyJournal of Trauma and Injury1738-87672287-16832019-06-0132211111410.20408/jti.2018.048988Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of LiteratureJayaramakrishna Depa0George Coritsidis1Department of Nephrology, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, NY, USADepartment of Nephrology, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, NY, USAMinimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD.http://www.jtraumainj.org/upload/pdf/jti-32-111.pdfminimal change diseaseskin injuryrecurrencenephrologyend-stage renal disease |
| spellingShingle | Jayaramakrishna Depa George Coritsidis Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature Journal of Trauma and Injury minimal change disease skin injury recurrence nephrology end-stage renal disease |
| title | Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature |
| title_full | Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature |
| title_fullStr | Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature |
| title_full_unstemmed | Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature |
| title_short | Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature |
| title_sort | recurrence of minimal change disease following a motor vehicle trauma an atypical cause and review of literature |
| topic | minimal change disease skin injury recurrence nephrology end-stage renal disease |
| url | http://www.jtraumainj.org/upload/pdf/jti-32-111.pdf |
| work_keys_str_mv | AT jayaramakrishnadepa recurrenceofminimalchangediseasefollowingamotorvehicletraumaanatypicalcauseandreviewofliterature AT georgecoritsidis recurrenceofminimalchangediseasefollowingamotorvehicletraumaanatypicalcauseandreviewofliterature |