Epigenetics disruptions enabled by porphyrin-derived metal-organic frameworks disarm resistances to sonocatalytic ROS anti-tumor actions

Epigenetics disruptions enabled by porphyrin-derived metal-organic frameworks disarm resistances to sonocatalytic ROS anti-tumor actions

Post-transcriptional epigenetic modifications provide numerous implications for tumor progression, metastasis and recurrence, which also pose resistances to reactive oxygen species (ROS)-based anti-tumor. Herein, we proposed an epigenetic deubiquitination disruption strategy to disarm the ubiquitina...

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Bibliographic Details
Main Authors: Yan Zhang, Dou Du, Chao Fang, Xin Yu, Yujia Fang, Xinyu Liu, Di Ou, Haohao Yin, Hui Liu, Taixia Wang, Lu Lu, Xiaolong Li, Kun Zhang
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2025-01-01
Series:Fundamental Research
Subjects:
Epigenetics engineering
Ubiquitylation modulation
Sonocatalysis
Reactive oxygen species resistance
Anti-tumor action
Online Access:http://www.sciencedirect.com/science/article/pii/S2667325822002977
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