Altered trial-to-trial responses to reward outcomes in KCNMA1 knockout mice during probabilistic learning tasks

Altered trial-to-trial responses to reward outcomes in KCNMA1 knockout mice during probabilistic learning tasks

Abstract The large-conductance calcium- and voltage-activated potassium (BK) channels, encoded by the KCNMA1 gene, play important roles in neuronal function. Mutations in KCNMA1 have been found in patients with various neurodevelopmental features, including intellectual disability, autism spectrum d...

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Bibliographic Details
Main Authors: Hiroyuki Ohta, Takashi Nozawa, Kohki Higuchi, Andrea L. Meredith, Yuji Morimoto, Yasushi Satoh, Toshiaki Ishizuka
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Behavioral and Brain Functions
Subjects:
BK channel
KCNMA1
Reinforcement learning
Win-stay-lose-shift
Learning rate
5-ABT
Online Access:https://doi.org/10.1186/s12993-024-00262-x
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