Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction

Objective To evaluate the longitudinal changes in the effective optical zone (EOZ) following hyperopic keratorefractive lenticule extraction (KLEx) and investigate factors influencing the EOZ.Patients and methods This retrospective study included 27 patients who underwent hyperopic KLEx. According t...

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Main Authors: Yangyi Huang, Dan Fu, Yuliang Wang, Xiaoliao Peng, Tian Han, Xingtao Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
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Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2453628
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author Yangyi Huang
Dan Fu
Yuliang Wang
Xiaoliao Peng
Tian Han
Xingtao Zhou
author_facet Yangyi Huang
Dan Fu
Yuliang Wang
Xiaoliao Peng
Tian Han
Xingtao Zhou
author_sort Yangyi Huang
collection DOAJ
description Objective To evaluate the longitudinal changes in the effective optical zone (EOZ) following hyperopic keratorefractive lenticule extraction (KLEx) and investigate factors influencing the EOZ.Patients and methods This retrospective study included 27 patients who underwent hyperopic KLEx. According to the transition zone (TZ) sizes, they were divided into two groups: group A (21 eyes) with a 2.0-mm TZ and group B (10 eyes) with a 0 or 0.2-mm TZ. The programmed treatment zone (PTZ) was the sum of the programmed optical zone (POZ) and the TZ.. Changes in the EOZ were evaluated at the early (within 1 month postoperatively) and late (over 6 months postoperatively) postoperative stages. The effects of the surgical and corneal topographic parameters on EOZ were explored.Results A significantly higher postoperative spherical equivalent was found in group B than in group A (p = 0.002). The early and late EOZ diameters were 4.27 ± 0.20 mm and 4.04 ± 0.21 mm in group A, and 3.48 ± 0.29 and 3.12 ± 0.49 mm in group B, respectively. ΔEOZ/POZ and ΔEOZ/PTZ were significantly larger at the late than the early postoperative stage in both groups (p < 0.001), with a larger ΔEOZ/POZ value in group B than that in group A at both stages (p < 0.001). EOZ reduction was negatively associated with POZ at the late postoperative stage (ΔEOZ/POZ: p = 0.043; ΔEOZ/PTZ: p = 0.020).Conclusions The EOZ continued decreasing following hyperopic KLEx. A larger TZ and POZ would result in a larger postoperative EOZ.
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spelling doaj-art-24bb4197f55d421dadcd897e8a01e1662025-01-17T17:05:50ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2025.2453628Changes in the effective optical zone following hyperopic keratorefractive lenticule extractionYangyi Huang0Dan Fu1Yuliang Wang2Xiaoliao Peng3Tian Han4Xingtao Zhou5Eye Institute and Department of Ophthalmology, Eye &amp; ENT Hospital, Fudan University, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye &amp; ENT Hospital, Fudan University, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye &amp; ENT Hospital, Fudan University, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye &amp; ENT Hospital, Fudan University, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye &amp; ENT Hospital, Fudan University, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye &amp; ENT Hospital, Fudan University, Shanghai, ChinaObjective To evaluate the longitudinal changes in the effective optical zone (EOZ) following hyperopic keratorefractive lenticule extraction (KLEx) and investigate factors influencing the EOZ.Patients and methods This retrospective study included 27 patients who underwent hyperopic KLEx. According to the transition zone (TZ) sizes, they were divided into two groups: group A (21 eyes) with a 2.0-mm TZ and group B (10 eyes) with a 0 or 0.2-mm TZ. The programmed treatment zone (PTZ) was the sum of the programmed optical zone (POZ) and the TZ.. Changes in the EOZ were evaluated at the early (within 1 month postoperatively) and late (over 6 months postoperatively) postoperative stages. The effects of the surgical and corneal topographic parameters on EOZ were explored.Results A significantly higher postoperative spherical equivalent was found in group B than in group A (p = 0.002). The early and late EOZ diameters were 4.27 ± 0.20 mm and 4.04 ± 0.21 mm in group A, and 3.48 ± 0.29 and 3.12 ± 0.49 mm in group B, respectively. ΔEOZ/POZ and ΔEOZ/PTZ were significantly larger at the late than the early postoperative stage in both groups (p < 0.001), with a larger ΔEOZ/POZ value in group B than that in group A at both stages (p < 0.001). EOZ reduction was negatively associated with POZ at the late postoperative stage (ΔEOZ/POZ: p = 0.043; ΔEOZ/PTZ: p = 0.020).Conclusions The EOZ continued decreasing following hyperopic KLEx. A larger TZ and POZ would result in a larger postoperative EOZ.https://www.tandfonline.com/doi/10.1080/07853890.2025.2453628Keratorefractive lenticule extraction (KLEx)hyperopiaeffective optical zonetransition zone
spellingShingle Yangyi Huang
Dan Fu
Yuliang Wang
Xiaoliao Peng
Tian Han
Xingtao Zhou
Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
Annals of Medicine
Keratorefractive lenticule extraction (KLEx)
hyperopia
effective optical zone
transition zone
title Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
title_full Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
title_fullStr Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
title_full_unstemmed Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
title_short Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
title_sort changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
topic Keratorefractive lenticule extraction (KLEx)
hyperopia
effective optical zone
transition zone
url https://www.tandfonline.com/doi/10.1080/07853890.2025.2453628
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